Coronaviruses—drug discovery and therapeutic options

A Zumla, JFW Chan, EI Azhar, DSC Hui… - Nature reviews Drug …, 2016 - nature.com
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …

Middle East respiratory syndrome coronavirus: a comprehensive review

MM Shehata, MR Gomaa, MA Ali, G Kayali - Frontiers of medicine, 2016 - Springer
Abstract The Middle East respiratory syndrome coronavirus was first identified in 2012 and
has since then remained uncontrolled. Cases have been mostly reported in the Middle East …

QSAR, molecular docking and molecular dynamics of 3c-like protease inhibitors

F LIN, XM FU, C WANG, SY JIANG… - Acta Physico …, 2016 - ingentaconnect.com
3C-like protease is an extremely important protease involved in the multiplicative process of
coronaviruses, including the deadlyMiddle East respiratory syndrome coronavirus (MERS …

3C-like 蛋白酶抑制剂的构效关系, 分子对接和分子动力学

林峰, 付新梅, 王超, 蒋思宇, 王景辉, 张述伟… - 物理化学 …, 2016 - whxb.pku.edu.cn
3C-like 蛋白酶是中东呼吸综合征冠状病毒(MERS-CoV) 等其它冠状病毒的繁殖过程中极为重要
的蛋白酶. 它已成为人类在抗冠状病毒领域中的研究热点. 本文基于计算生物学方法对与MERS …

[PDF][PDF] Bioscience and Bioengineering Communications

MERS Coronavirus, ITT Progressions - academia.edu
Abstract The recently emerged Middle East Respiratory Syndrome Coronavirus (MERS-
CoV) causing severe respiratory tract infection in humans is now considered as a pandemic …