Enhanced n-wheeler post accidental rescue system connecting to the correct person at the correct time

A Parashar, V Maheshwari… - 2016 IEEE Region 10 …, 2016 - ieeexplore.ieee.org
Automobile Technology now-a-days is growing very quickly, and this incredible growth has
definitely made our lives better than before. This growth in technology has also increased …

Small molecules for active targeting in cancer

CS Kue, A Kamkaew, K Burgess… - Medicinal research …, 2016 - Wiley Online Library
For the purpose of this review, active targeting in cancer research encompasses strategies
wherein a ligand for a cell surface receptor expressed on tumor cells is used to deliver a …

Biodistribution of [68Ga]PSMA-HBED-CC in Patients with Prostate Cancer: Characterization of Uptake in Normal Organs and Tumour Lesions

V Prasad, IG Steffen, G Diederichs… - Molecular imaging and …, 2016 - Springer
Purpose The aim of this study was to determine the physiological and pathophysiological
biodistribution of [68 Ga] PSMA-HBED-CC (PSMA-11)([68 Ga] PSMA) in patients with …

The therapeutic and diagnostic potential of the prostate specific membrane antigen/glutamate carboxypeptidase II (PSMA/GCPII) in cancer and neurological disease

JC Evans, M Malhotra, JF Cryan… - British journal of …, 2016 - Wiley Online Library
Prostate specific membrane antigen (PSMA) otherwise known as glutamate
carboxypeptidase II (GCPII) is a membrane bound protein that is highly expressed in …

Radiolabeled enzyme inhibitors and binding agents targeting PSMA: effective theranostic tools for imaging and therapy of prostate cancer

MRA Pillai, R Nanabala, A Joy, A Sasikumar… - Nuclear medicine and …, 2016 - Elsevier
Because of the broad incidence, morbidity and mortality associated with prostate-derived
cancer, the development of more effective new technologies continues to be an important …

Prostate-specific membrane antigen (PSMA)-mediated laminin proteolysis generates a pro-angiogenic peptide

RE Conway, C Rojas, J Alt, Z Nováková… - Angiogenesis, 2016 - Springer
Prostate-specific membrane antigen (PSMA) is a membrane-bound glutamate
carboxypeptidase expressed in a number of tissues. PSMA participates in various biological …

Small-molecule PSMA ligands. Current state, SAR and perspectives

AE Machulkin, YA Ivanenkov… - Journal of drug …, 2016 - Taylor & Francis
Prostate cancer (PC) is the prevalent malignancy widespread among men in the Western
World. Prostate specific membrane antigen (PSMA) is an established PC marker and has …

Folate-targeted amphiphilic cyclodextrin. siRNA nanoparticles for prostate cancer therapy exhibit PSMA mediated uptake, therapeutic gene silencing in vitro and …

JC Evans, M Malhotra, J Guo, JP O'Shea… - … , Biology and Medicine, 2016 - Elsevier
In this study, a folate targeted cyclodextrin (CD) nanoparticle was prepared by co-
formulating CD. siRNA complexes with DSPE-PEG 5000-folate to target the prostate specific …

Induction of PSMA and Internalization of an Anti-PSMA mAb in the Vascular Compartment

DP Nguyen, PL Xiong, H Liu, S Pan, W Leconet… - Molecular Cancer …, 2016 - AACR
Angiogenesis is critical for tumor growth and survival and involves interactions between
cancer and endothelial cells. Prostate-specific membrane antigen (PSMA/FOLH1) is …

Preparation of [68Ga] PSMA-11 for PET–CT imaging using a manual synthesis module and organic matrix based 68Ge/68Ga generator

R Nanabala, MK Anees, A Sasikumar, A Joy… - Nuclear medicine and …, 2016 - Elsevier
Abstract Introduction [68 Ga] PSMA-11 is a relatively recently introduced
radiopharmaceutical for PET–CT imaging of prostate cancer patients. The availability of 68 …