[PDF][PDF] Identifiability of large nonlinear biochemical networks
AF Villaverde, A Barreiro - MATCH Commun. Math. Comput …, 2016 - researchgate.net
Dynamic models formulated as a set of ordinary differential equations provide a detailed
description of the time-evolution of a system. Such models of (bio) chemical reaction …
description of the time-evolution of a system. Such models of (bio) chemical reaction …
Numerical algebraic geometry for model selection and its application to the life sciences
Researchers working with mathematical models are often confronted by the related
problems of parameter estimation, model validation and model selection. These are all …
problems of parameter estimation, model validation and model selection. These are all …
Discrimination between competing model structures of biological systems in the presence of population heterogeneity
M Martin-Casas, A Mesbah - IEEE life sciences letters, 2016 - ieeexplore.ieee.org
Computational models are useful for quantitative elucidation of the dynamical behavior of
biological systems. Oftentimes, several competing models (ie, hypotheses) are proposed to …
biological systems. Oftentimes, several competing models (ie, hypotheses) are proposed to …
Set-based experiment design for model discrimination using bilevel optimization
N Rudolph, S Streif, R Findeisen - IFAC-PapersOnLine, 2016 - Elsevier
Experiment design can be used to discriminate between valid and invalid models. This task
is not trivial as models are typically nonlinear and the kinetic parameters and initial …
is not trivial as models are typically nonlinear and the kinetic parameters and initial …