Workflow-driven clinical decision support for personalized oncology
A Bucur, J van Leeuwen, N Christodoulou… - BMC medical informatics …, 2016 - Springer
Background The adoption in oncology of Clinical Decision Support (CDS) may help clinical
users to efficiently deal with the high complexity of the domain, lead to improved patient …
users to efficiently deal with the high complexity of the domain, lead to improved patient …
Pharmacokinetic modeling of a gel-delivered dapivirine microbicide in humans
ME Halwes, JM Steinbach-Rankins… - European Journal of …, 2016 - Elsevier
Although a number of drugs have been developed for the treatment and prevention of
human immunodeficiency virus (HIV) infection, it has proven difficult to optimize the drug and …
human immunodeficiency virus (HIV) infection, it has proven difficult to optimize the drug and …
A Modular Repository-based Infrastructure for Simulation Model Storage and Execution Support in the Context of In Silico Oncology and In Silico Medicine
NA Christodoulou, NE Tousert… - Cancer …, 2016 - journals.sagepub.com
The plethora of available disease prediction models and the ongoing process of their
application into clinical practice–following their clinical validation–have created new needs …
application into clinical practice–following their clinical validation–have created new needs …
A mathematical model for growth of solid tumors and combination therapy with an application to colorectal cancer
V De Mattei, F Flandoli, M Leocata, MC Polito… - arXiv preprint arXiv …, 2016 - arxiv.org
We present a mathematical model, based on ordinary differential equations, for the evolution
of solid tumors and their response to treatment. Specifically the effects of a cytotoxic agent …
of solid tumors and their response to treatment. Specifically the effects of a cytotoxic agent …