Testosterone and cardiovascular disease

RA Kloner, C Carson, A Dobs, S Kopecky… - Journal of the American …, 2016 - jacc.org
Testosterone (T) is the principal male sex hormone. As men age, T levels typically fall.
Symptoms of low T include decreased libido, vasomotor instability, and decreased bone …

Diagnosis and treatment of testosterone deficiency: recommendations from the Fourth International Consultation for Sexual Medicine (ICSM 2015)

M Khera, G Adaikan, J Buvat, S Carrier… - The journal of sexual …, 2016 - academic.oup.com
Introduction Testosterone deficiency (TD), also known as hypogonadism, is a condition
affecting a substantial proportion of men as they age. The diagnosis and management of TD …

Effects of testosterone treatment in older men

PJ Snyder, S Bhasin, GR Cunningham… - … England Journal of …, 2016 - Mass Medical Soc
Background Serum testosterone concentrations decrease as men age, but benefits of
raising testosterone levels in older men have not been established. Methods We assigned …

Testosterone treatment and risk of venous thromboembolism: population based case-control study

C Martinez, S Suissa, S Rietbrock, A Katholing… - bmj, 2016 - bmj.com
Objective To determine the risk of venous thromboembolism associated with use of
testosterone treatment in men, focusing particularly on the timing of the risk. Design …

Survival and cardiovascular events in men treated with testosterone replacement therapy: an intention-to-treat observational cohort study

CJD Wallis, K Lo, Y Lee, Y Krakowsky… - The lancet Diabetes & …, 2016 - thelancet.com
Background Conflicting evidence exists for the association between testosterone
replacement therapy and mortality and cardiovascular events. The US Food and Drug …

Muscle-bone interactions: From experimental models to the clinic? A critical update

MR Laurent, V Dubois, F Claessens… - Molecular and cellular …, 2016 - Elsevier
Bone is a biomechanical tissue shaped by forces from muscles and gravitation.
Simultaneous bone and muscle decay and dysfunction (osteosarcopenia or sarco …

Fundamental concepts regarding testosterone deficiency and treatment: international expert consensus resolutions

A Morgentaler, M Zitzmann, AM Traish, AW Fox… - Mayo Clinic …, 2016 - Elsevier
To address widespread concerns regarding the medical condition of testosterone (T)
deficiency (TD)(male hypogonadism) and its treatment with T therapy, an international …

Impact of testosterone replacement therapy on myocardial infarction, stroke, and death in men with low testosterone concentrations in an integrated health care system

JL Anderson, HT May, DL Lappé, T Bair, V Le… - The American journal of …, 2016 - Elsevier
The aim of this study was to assess the effect of testosterone replacement therapy (TRT) on
cardiovascular outcomes. Men (January 1, 1996, to December 31, 2011) with a low initial …

Endogenous and exogenous testosterone and the risk of prostate cancer and increased prostate‐specific antigen (PSA) level: a meta‐analysis

P Boyle, A Koechlin, M Bota, A d'Onofrio… - BJU …, 2016 - Wiley Online Library
Objective To review and quantify the association between endogenous and exogenous
testosterone and prostate‐specific antigen (PSA) and prostate cancer. Methods Literature …

[HTML][HTML] Treatment of men for “low testosterone”: a systematic review

S Huo, AR Scialli, S McGarvey, E Hill, B Tügertimur… - PloS one, 2016 - journals.plos.org
Testosterone products are recommended by some prescribers in response to a diagnosis or
presumption of “low testosterone”(low-T) for cardiovascular health, sexual function, muscle …