The frequency of influenza and bacterial coinfection: a systematic review and meta‐analysis

EY Klein, B Monteforte, A Gupta… - Influenza and other …, 2016 - Wiley Online Library
Aim Coinfecting bacterial pathogens are a major cause of morbidity and mortality in
influenza. However, there remains a paucity of literature on the magnitude of coinfection in …

Early-life origins of chronic obstructive pulmonary disease

FD Martinez - New England Journal of Medicine, 2016 - Mass Medical Soc
Early-Life Origins of Chronic Obstructive Pulmonary Disease | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

Comprehensive molecular testing for respiratory pathogens in community-acquired pneumonia

NJ Gadsby, CD Russell, MP McHugh… - Clinical Infectious …, 2016 - academic.oup.com
Background. The frequent lack of a microbiological diagnosis in community-acquired
pneumonia (CAP) impairs pathogen-directed antimicrobial therapy. This study assessed the …

Microbial etiology of pneumonia: epidemiology, diagnosis and resistance patterns

C Cilloniz, I Martin-Loeches, C Garcia-Vidal… - International journal of …, 2016 - mdpi.com
Globally, pneumonia is a serious public health concern and a major cause of mortality and
morbidity. Despite advances in antimicrobial therapies, microbiological diagnostic tests and …

Staphylococcus aureus Community-acquired Pneumonia: Prevalence, Clinical Characteristics, and Outcomes

WH Self, RG Wunderink, DJ Williams… - Reviews of Infectious …, 2016 - academic.oup.com
Abstract Background. Prevalence of Staphylococcus aureus community-acquired
pneumonia (CAP) and its clinical features remain incompletely understood, complicating …

Unbiased detection of respiratory viruses by use of RNA sequencing-based metagenomics: a systematic comparison to a commercial PCR panel

EH Graf, KE Simmon, KD Tardif, W Hymas… - Journal of clinical …, 2016 - Am Soc Microbiol
Current infectious disease molecular tests are largely pathogen specific, requiring test
selection based on the patient's symptoms. For many syndromes caused by a large number …

Viral infection in community-acquired pneumonia: a systematic review and meta-analysis

M Burk, K El-Kersh, M Saad, T Wiemken… - European …, 2016 - Eur Respiratory Soc
The advent of PCR has improved the identification of viruses in patients with community-
acquired pneumonia (CAP). Several studies have used PCR to establish the importance of …

Laboratory diagnosis of pneumonia in the molecular age

A Torres, N Lee, C Cilloniz, J Vila… - European …, 2016 - Eur Respiratory Soc
Pneumonia remains a worldwide health problem with a high rate of morbidity and mortality.
Identification of microbial pathogens which cause pneumonia is an important area for …

Update on human rhinovirus and coronavirus infections

SB Greenberg - Seminars in respiratory and critical care …, 2016 - thieme-connect.com
Human rhinovirus (HRV) and coronavirus (HCoV) infections are associated with both upper
respiratory tract illness (“the common cold”) and lower respiratory tract illness (pneumonia) …

Antibiotic therapy for adults hospitalized with community-acquired pneumonia: a systematic review

JS Lee, DL Giesler, WF Gellad, MJ Fine - Jama, 2016 - jamanetwork.com
Importance Antibiotic therapy is the cornerstone of medical management for community-
acquired pneumonia. Objective To assess the associations between 3 key aspects of …