[HTML][HTML] Coronaviruses—drug discovery and therapeutic options

A Zumla, JFW Chan, EI Azhar, DSC Hui… - Nature reviews Drug …, 2016 - nature.com
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …

[HTML][HTML] Structure, function, and evolution of coronavirus spike proteins

F Li - Annual review of virology, 2016 - annualreviews.org
The coronavirus spike protein is a multifunctional molecular machine that mediates
coronavirus entry into host cells. It first binds to a receptor on the host cell surface through its …

Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination

JA Otter, C Donskey, S Yezli, S Douthwaite… - Journal of hospital …, 2016 - Elsevier
Viruses with pandemic potential including H1N1, H5N1, and H5N7 influenza viruses, and
severe acute respiratory syndrome (SARS)/Middle East respiratory syndrome (MERS) …

Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia

JSM Sabir, TTY Lam, MMM Ahmed, L Li, Y Shen… - Science, 2016 - science.org
Outbreaks of Middle East respiratory syndrome (MERS) raise questions about the
prevalence and evolution of the MERS coronavirus (CoV) in its animal reservoir. Our …

Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection

OW Ng, A Chia, AT Tan, RS Jadi, HN Leong… - Vaccine, 2016 - Elsevier
Severe acute respiratory syndrome (SARS) is a highly contagious infectious disease which
first emerged in late 2002, caused by a then novel human coronavirus, SARS coronavirus …

Efficacy of an automated multiple emitter whole-room ultraviolet-C disinfection system against coronaviruses MHV and MERS-CoV

K Bedell, AH Buchaklian, S Perlman - infection control & hospital …, 2016 - cambridge.org
Efficient and automated methods of disinfecting surfaces contaminated with the Middle
Eastern respiratory syndrome coronavirus (MERS-CoV) may prevent the spread of the virus …

[HTML][HTML] Structure of main protease from human coronavirus NL63: insights for wide spectrum anti-coronavirus drug design

F Wang, C Chen, W Tan, K Yang, H Yang - Scientific reports, 2016 - nature.com
Abstract First identified in The Netherlands in 2004, human coronavirus NL63 (HCoV-NL63)
was found to cause worldwide infections. Patients infected by HCoV-NL63 are typically …

[HTML][HTML] Cellular entry of the porcine epidemic diarrhea virus

W Li, FJM van Kuppeveld, Q He, PJM Rottier, BJ Bosch - Virus research, 2016 - Elsevier
Porcine epidemic diarrhea virus (PEDV), a coronavirus discovered more than 40 years ago,
regained notoriety recently by its devastating outbreaks in East Asia and the Americas …

[HTML][HTML] Treatment outcomes for patients with Middle Eastern Respiratory Syndrome Coronavirus (MERS CoV) infection at a coronavirus referral center in the Kingdom …

M Al Ghamdi, KM Alghamdi, Y Ghandoora… - BMC infectious …, 2016 - Springer
Abstract Background Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV) is a
poorly understood disease with no known treatments. We describe the clinical features and …

Link of a ubiquitous human coronavirus to dromedary camels

VM Corman, I Eckerle, ZA Memish… - Proceedings of the …, 2016 - National Acad Sciences
The four human coronaviruses (HCoVs) are globally endemic respiratory pathogens. The
Middle East respiratory syndrome (MERS) coronavirus (CoV) is an emerging CoV with a …