Metabolomics is an emerging'omics' science involving the comprehensive characterization
of metabolites and metabolism in biological systems. Recent advances in metabolomics …

BACKGROUND There is a clinical need for new technologies that would enable rapid
disease diagnosis based on diagnostic molecular signatures. Ambient ionization mass …

Examination of tissue sections using desorption electrospray ionization (DESI)-MS revealed
phospholipid-derived signals that differ between gray matter, white matter, gliomas …

Imaging Mass Spectrometry (IMS) is strengthening its position as a valuable analytical tool. It
has unique ability to identify structures and to unravel molecular changes that occur in the …

Increasingly abundant food fraud cases have brought food authenticity and safety into major
focus. This study presents a fast and effective way to identify meat products using rapid …

Here we describe a new instrument (SpiderMass) designed for in vivo and real-time
analysis. In this instrument ion production is performed remotely from the MS instrument and …

Background The term 'metabolome'was introduced to the scientific literature in September
1998. Aim and key scientific concepts of the review To mark its 18-year-old 'coming of age' …

Inborn errors of metabolism (IEM) represent a group of about 500 rare genetic diseases with
an overall estimated incidence of 1/2500. The diversity of metabolic pathways involved …

Introduction Cellular metabolism is altered during cancer initiation and progression, which
allows cancer cells to increase anabolic synthesis, avoid apoptosis and adapt to low nutrient …

Ambien ionization and miniaturization of mass spectrometers are two fields in mass
spectrometry that have advanced significantly in the last decade. The integration of the …