The NMDA receptor and schizophrenia: from pathophysiology to treatment

DT Balu - Advances in pharmacology, 2016 - Elsevier
Schizophrenia is a severe mental illness that affects almost 1% of the population worldwide.
Even though the etiology of schizophrenia is uncertain, it is believed to be a …

Adult neurogenesis and psychiatric disorders

E Kang, Z Wen, H Song… - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Psychiatric disorders continue to be among the most challenging disorders to diagnose and
treat because there is no single genetic or anatomical locus that is causative for the disease …

Progress and future directions in research on the psychosis prodrome: a review for clinicians

KA Woodberry, DI Shapiro, C Bryant… - Harvard review of …, 2016 - journals.lww.com
The psychosis prodrome, or period of clinical and functional decline leading up to acute
psychosis, offers a unique opportunity for identifying mechanisms of psychosis onset and for …

Impairments in dendrite morphogenesis as etiology for neurodevelopmental disorders and implications for therapeutic treatments

T Copf - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Dendrite morphology is pivotal for neural circuitry functioning. While the causative
relationship between small-scale dendrite morphological abnormalities (shape, density of …

Genetic consideration of schizotypal traits: A review

EE Walter, F Fernandez, M Snelling… - Frontiers in …, 2016 - frontiersin.org
Schizotypal traits are of interest and importance in their own right and also have theoretical
and clinical associations with schizophrenia. These traits comprise attenuated psychotic …

Using evolutionary theory to guide mental health research

Z Durisko, BH Mulsant, K McKenzie… - … Canadian Journal of …, 2016 - journals.sagepub.com
Evolutionary approaches to medicine can shed light on the origins and etiology of disease.
Such an approach may be especially useful in psychiatry, which frequently addresses …

Cingulo-opercular network efficiency mediates the association between psychotic-like experiences and cognitive ability in the general population

JM Sheffield, S Kandala, GC Burgess… - Biological psychiatry …, 2016 - Elsevier
Background Psychosis is hypothesized to occur on a spectrum between psychotic disorders
and health in individuals. In the middle of the spectrum are individuals who endorse …

Brain-derived neurotrophic factor gene Val66Met polymorphism and risk of schizophrenia: a meta-analysis of case–control studies

M Kheirollahi, E Kazemi, S Ashouri - Cellular and Molecular Neurobiology, 2016 - Springer
According to evidences from previous family and association studies, it has been claimed
that genetic factors are involved in the neuropathogenesis of Schizophrenia disorder …

A systematic review of the neurobiological underpinnings of borderline personality disorder (BPD) in childhood and adolescence

C Winsper, S Marwaha, ST Lereya… - Reviews in the …, 2016 - degruyter.com
Contemporary theories for the aetiology of borderline personality disorder (BPD) take a
lifespan approach asserting that inborn biological predisposition is potentiated across …

Unitary construct of generalized cognitive ability underlying BACS performance across psychotic disorders and in their first-degree relatives

WC Hochberger, SK Hill, CLM Nelson, JL Reilly… - Schizophrenia …, 2016 - Elsevier
Despite robust evidence of neurocognitive dysfunction in psychotic patients, the degree of
similarity in cognitive architecture across psychotic disorders and among their respective first …