Glutamine synthetase: role in neurological disorders

AR Jayakumar, MD Norenberg - The glutamate/GABA-glutamine cycle …, 2016 - Springer
Glutamine synthetase (GS) is an ATP-dependent enzyme found in most species that
synthesizes glutamine from glutamate and ammonia. In brain, GS is exclusively located in …

The glutamate–glutamine cycle in epilepsy

T Eid, SE Gruenbaum, R Dhaher, TSW Lee… - The Glutamate/GABA …, 2016 - Springer
Epilepsy is a complex, multifactorial disease characterized by spontaneous recurrent
seizures and an increased incidence of comorbid conditions such as anxiety, depression …

A sub-threshold dose of pilocarpine increases glutamine synthetase in reactive astrocytes and enhances the progression of amygdaloid-kindling epilepsy in rats

HL Sun, DP Deng, XH Pan, CY Wang, XL Zhang… - …, 2016 - journals.lww.com
Materials and methods For our study, we obtained 198 male Sprague–Dawley rats (200–
220 g). Under anesthesia, an electrode was implanted into the right basolateral amygdala …

Transcriptoma del núcleo desencadenante de las crisis epilépticas en el hámster GASH: Sal

D López López - 2016 - gredos.usal.es
[ES] La línea de hámster sirios (Mesocricetus auratus) GASH: Sal (Genetic audiogenic
seizures hamster Salamanca) desarrollada en el bioterio de la Universidad de Salamanca …