Ursolic acid and oleanolic acid: pentacyclic terpenoids with promising anti-inflammatory activities
Background: Plant derived products are not only served as dietary components but also
used to treat and prevent the inflammatory associated diseases like cancer. Among the …
used to treat and prevent the inflammatory associated diseases like cancer. Among the …
Molecular mechanisms of action of quercetin in cancer: recent advances
In the last few decades, the scientific community has discovered an immense potential of
natural compounds in the treatment of dreadful diseases such as cancer. Besides the …
natural compounds in the treatment of dreadful diseases such as cancer. Besides the …
Molecular mechanisms underlying chemopreventive potential of curcumin: Current challenges and future perspectives
In recent years, natural compounds have received considerable attention in preventing and
curing most dreadful diseases including cancer. The reason behind the use of natural …
curing most dreadful diseases including cancer. The reason behind the use of natural …
Molecular targets of gambogic acid in cancer: recent trends and advancements
Natural compounds have been known as biosafety agents for their significant clinical and
biological activity against dreadful diseases, including cancer, cardiovascular, and …
biological activity against dreadful diseases, including cancer, cardiovascular, and …
Biosynthesis of structurally diverse triterpenes in plants: the role of oxidosqualene cyclases
S Ghosh - 2016 - insajournal.in
Triterpenes, thirty-carbon compounds derived from five-carbon isoprene units, are among
the largest and diverse classes of natural products. To date, over 20,000 distinct triterpene …
the largest and diverse classes of natural products. To date, over 20,000 distinct triterpene …
[HTML][HTML] Application of omics technologies for evaluation of antibacterial mechanisms of action of plant-derived products
In the face of increasing bacterial resistance to antibiotics currently in use, the search for
new antimicrobial agents has received a boost in recent years, with natural products playing …
new antimicrobial agents has received a boost in recent years, with natural products playing …
Synthesis and cytotoxic activity of novel A-ring cleaved ursolic acid derivatives in human non-small cell lung cancer cells
VIS Mendes, GA Bartholomeusz, M Ayres… - European journal of …, 2016 - Elsevier
Ursolic acid (UA) is a pentacyclic triterpenoid with recognized anticancer properties. We
prepared a series of new A-ring cleaved UA derivatives and evaluated their antiproliferative …
prepared a series of new A-ring cleaved UA derivatives and evaluated their antiproliferative …
[HTML][HTML] Kazakh Ziziphora Species as Sources of Bioactive Substances
K Šmejkal, M Malaník, K Zhaparkulova, Z Sakipova… - Molecules, 2016 - mdpi.com
Ziziphora species represent the prototypical example of the Lamiaceae family. The
phytochemicals present in Ziziphora include monoterpenic essential oils, triterpenes and …
phytochemicals present in Ziziphora include monoterpenic essential oils, triterpenes and …
[HTML][HTML] A novel co-drug of aspirin and ursolic acid interrupts adhesion, invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFR …
Metastasis currently remains the predominant cause of breast carcinoma treatment failure.
The effective targeting of metastasis-related-pathways in cancer holds promise for a new …
The effective targeting of metastasis-related-pathways in cancer holds promise for a new …
[HTML][HTML] Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1α
J Shan, Y Xuan, Q Zhang, J Huang - Journal of Zhejiang University …, 2016 - ncbi.nlm.nih.gov
Objective: To explore the efficacy of ursolic acid in sensitizing colon cancer cells to
chemotherapy under hypoxia and its underlying mechanisms. Methods: Three colon cancer …
chemotherapy under hypoxia and its underlying mechanisms. Methods: Three colon cancer …