Introduction and enzootic of A/H5N1 in Egypt: Virus evolution, pathogenicity and vaccine efficacy ten years on

EM Abdelwhab, MK Hassan, AS Abdel-Moneim… - Infection, Genetics and …, 2016 - Elsevier
It is almost a decade since the highly pathogenic H5N1 avian influenza virus (A/H5N1) of
clade 2.2. 1 was introduced to Egypt in 2005, most likely, via wild birds; marking the longest …

[HTML][HTML] Avian influenza A (H5N1) virus in Egypt

G Kayali, A Kandeil, R El-Shesheny… - Emerging infectious …, 2016 - ncbi.nlm.nih.gov
In Egypt, avian influenza A subtype H5N1 and H9N2 viruses are enzootic in poultry. The
control plan devised by veterinary authorities in Egypt to prevent infections in poultry …

[HTML][HTML] Novel polymerase gene mutations for human adaptation in clinical isolates of avian H5N1 influenza viruses

Y Arai, N Kawashita, T Daidoji, MS Ibrahim… - PLoS …, 2016 - journals.plos.org
A major determinant in the change of the avian influenza virus host range to humans is the
E627K substitution in the PB2 polymerase protein. However, the polymerase activity of avian …

[HTML][HTML] Phylodynamics of avian influenza clade 2.2. 1 H5N1 viruses in Egypt

A Arafa, I El-Masry, S Kholosy, MK Hassan, G Dauphin… - Virology journal, 2016 - Springer
Background Highly pathogenic avian influenza (HPAI) viruses of the H5N1 subtype are
widely distributed within poultry populations in Egypt and have caused multiple human …

Re-emergence of amantadine-resistant variants among highly pathogenic avian influenza H5N1 viruses in Egypt

R El-Shesheny, O Bagato, A Kandeil, A Mostafa… - Infection, Genetics and …, 2016 - Elsevier
Highly pathogenic avian influenza (HPAI) H5N1 virus continues to undergo substantial
evolution. Emergence of antiviral resistance among H5N1 avian influenza viruses is a major …

Genetic characterization of highly pathogenic avian influenza H5N1 viruses isolated from naturally infected pigeons in Egypt

EM Elgendy, Y Watanabe, T Daidoji, Y Arai, K Ikuta… - Virus Genes, 2016 - Springer
Avian influenza viruses impose serious public health burdens with significant mortality and
morbidity not only in poultry but also in humans. While poultry susceptibility to avian …

[HTML][HTML] Risk assessment of recent Egyptian H5N1 influenza viruses

AS Arafa, S Yamada, M Imai, T Watanabe… - Scientific reports, 2016 - nature.com
Highly pathogenic avian influenza (HPAI) viruses of the H5N1 subtype are enzootic in
poultry populations in different parts of the world, and have caused numerous human …

Evolutionary features of influenza A/H5N1 virus populations in Egypt: poultry and human health implications

MM Naguib, EM Abdelwhab, TC Harder - Archives of virology, 2016 - Springer
Since 2006, in Egypt, highly pathogenic avian influenza virus (HPAIV) H5N1 has
established endemic status in poultry. Bayesian evolutionary analysis sampling trees …

The matrix gene of influenza A H5N1 in Egypt, 2006–2016: molecular insights and distribution of amantadine-resistant variants

MM Naguib, N Hagag, AA El-Sanousi, HA Hussein… - Virus genes, 2016 - Springer
Large-scale sequence analysis of Matrix (M) gene and its coding proteins M1 and M2 was
performed for 274 highly pathogenic avian influenza viruses H5N1 circulated in Egypt from …

Active surveillance of avian influenza viruses in Egyptian poultry, 2015

AS Kayed, A Kandeil, R El Shesheny, MA Ali… - EMHJ-Eastern …, 2016 - apps.who.int
Surveillance for avian influenza viruses in Egyptian poultry has been conducted since 2009.
Up to 2011, all the detected viruses were H5N1, and the overall prevalence was 5%. In …