Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are uniquely
required to balance the formation of new blood vessels with the maintenance and …

The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …

In addition to their conventional role as a conduit system for gases, nutrients, waste products
or cells, blood vessels in the skeletal system play active roles in controlling multiple aspects …

Hypoxic tumor-associated macrophages (TAMs) acquire angiogenic and
immunosuppressive properties. Yet it remains unknown if metabolic changes influence …

Angiogenesis, the formation of new blood vessels from pre-existing vasculature, plays a vital
role in physiological and pathological processes (embryonic development, wound healing …

Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

Glioblastoma multiforme (GBM) is treated by surgical resection followed by
radiochemotherapy. Bevacizumab is commonly deployed for anti‐angiogenic therapy of …

The characterization of oesophageal and gastric cancer into subtypes based on genotype
has evolved in the past decade. Insights into the molecular landscapes of gastroesophageal …

Interaction of numerous signaling pathways in endothelial and mesangial cells results in
exquisite control of the process of physiological angiogenesis, with a central role played by …

Approaches to the management of portal hypertension and variceal hemorrhage in
pediatrics remain controversial, in large part because they are not well informed by rigorous …