A review on the efficacy and toxicity of different doxorubicin nanoparticles for targeted therapy in metastatic breast cancer

A Shafei, W El-Bakly, A Sobhy, O Wagdy… - Biomedicine & …, 2017 - Elsevier
In metastatic breast cancer (MBC), the conventional doxorubicin (DOX) has various
problems due to lack of selectivity with subsequent therapeutic failure and adverse effects …

Mammographic density and ageing: a collaborative pooled analysis of cross-sectional data from 22 countries worldwide

A Burton, G Maskarinec, B Perez-Gomez… - PLoS …, 2017 - journals.plos.org
Background Mammographic density (MD) is one of the strongest breast cancer risk factors.
Its age-related characteristics have been studied in women in western countries, but …

Air pollution, UV irradiation and skin carcinogenesis: what we know, where we stand and what is likely to happen in the future?

B Zegarska, K Pietkun, W Zegarski, P Bolibok… - … in Dermatology and …, 2017 - termedia.pl
The link between air pollution, UV irradiation and skin carcinogenesis has been
demonstrated within a large number of epidemiological studies. Many have shown the …

Leptin is overexpressed in the tumor microenvironment of obese patients with estrogen receptor positive breast cancer

M Hosney, S Sabet, M El‑Shinawi… - Experimental and …, 2017 - spandidos-publications.com
The present study aimed to investigate the potential role of leptin in the progression of breast
cancer and the associated cell proliferation signalling pathway (s). A total of 44 female …

[HTML][HTML] Validation of a serum microRNA panel as biomarkers for early diagnosis of hepatocellular carcinoma post-hepatitis C infection in Egyptian patients

MN Elemeery, AN Badr, MA Mohamed… - World Journal of …, 2017 - ncbi.nlm.nih.gov
AIM To investigate the prospective importance of serum micro (mi) RNAs (miR-125b, miR-
138b, miR-1269, miR-214-5p, miR-494, miR375 and miR-145) as early biomarkers for the …

Angiopoietin-like protein 3 and 4 expression 4 and their serum levels in hepatocellular carcinoma

S Amal, HE Zidan, NM Rashad, FM Wadea - Cytokine, 2017 - Elsevier
Background Hepatocellular carcinoma (HCC) is the 6th most common cancer and the 3rd
leading cause of cancer causing death allover the world. The aim of this research to explore …

Enhanced anticancer effect and reduced toxicity of doxorubicin in combination with thymoquinone released from poly-N-acetyl glucosamine nanomatrix in mice …

NE El-Ashmawy, EG Khedr, EZM Ebeid… - European Journal of …, 2017 - Elsevier
The incidence of breast cancer remarkably increases all over the world. Therefore, there is a
great demand to introduce new approaches into cancer treatment field. The current study …

Breast cancer in women aging 35 years old and younger: The Egyptian National Cancer Institute (NCI) experience

AD Darwish, AM Helal, NHA El-Din, LL Solaiman… - The Breast, 2017 - Elsevier
Objective The aim is to identify the epidemiological and clinicopathological features
associated with young breast cancer (BC) patients and to discuss factors affecting tumor …

Metformin augments doxorubicin cytotoxicity in mammary carcinoma through activation of adenosine monophosphate protein kinase pathway

NE El-Ashmawy, NF Khedr, HA El-Bahrawy… - Tumor …, 2017 - journals.sagepub.com
Since the incidence of breast cancer increases dramatically all over the world, the search for
effective treatment is an urgent need. Metformin has demonstrated anti-tumorigenic effect …

MicroRNA-181a and its target Smad 7 as potential biomarkers for tracking child acute lymphoblastic leukemia

M Nabhan, ML Louka, E Khairy, F Tash, R Ali-Labib… - Gene, 2017 - Elsevier
Acute lymphoblastic leukemia (ALL) is the most common pediatric hematologic tumor. MiR-
181a was expected to have a role in the development of hematological malignancies; it …