Parkinson's disease (PD) is a chronic and progressive disorder characterized
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …

Symptoms of Parkinson's disease arise due to neuronal loss in multiple brain regions,
especially dopaminergic neurons in the substantia nigra pars compacta. Current therapies …

Parkinson's disease (PD) is characterized by α-synuclein accumulation, dopaminergic
neuron loss and inflammation. α-Synuclein can be secreted by neurons and activate …

Alzheimer's and Parkinson's diseases are the most prevalent neurodegenerative diseases
that generate important health-related direct and indirect socio-economic costs. They are …

Intracellular accumulation of α-synuclein (α-syn) are hallmarks of synucleinopathies,
including Parkinson's disease (PD). Exogenous addition of preformed α-syn fibrils (PFFs) …

Parkinson's disease is one of the several neurodegenerative disorders that affects aging
individuals, with approximately 1% of those over the age of 60 years developing the disorder …

Microglia are considered to be the resident immune cells of the central nervous system and
contribute significantly to ongoing neuroinflammation in a variety of neurodegenerative …

Alzheimer's disease (AD) and Parkinson's disease (PD) are debilitating, incurable
neurodegenerative disorders. Intensive research efforts have been focused on …

The current review deals with the involvement of glycogen synthase kinase-3 (GSK-3) in
major neurodegenerative disorders like Alzheimer's Disease (AD), Cerebral ischemia …

'Involuntary tremulous motion, with lessened muscular power, in parts not in action and even
when supported; with propensity to bend the trunk forwards, and to pass from a walking to a …