Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2017 - Elsevier
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has continued
development and standardization of methodologies for biomarkers and has provided an …

Cortisol: mediator of association between Alzheimer's disease and diabetes mellitus?

E Notarianni - Psychoneuroendocrinology, 2017 - Elsevier
Numerous epidemiologic studies have identified an independent association between
Alzheimer's disease (AD) and diabetes mellitus (DM), which remains unexplained. This …

Plasma cortisol, brain amyloid-β, and cognitive decline in preclinical alzheimer's disease: a 6-year prospective cohort study

RH Pietrzak, SM Laws, YY Lim, SJ Bender… - Biological Psychiatry …, 2017 - Elsevier
Background Hypothalamic-pituitary-adrenal axis dysregulation, which is typically assessed
by measuring cortisol levels, is associated with cognitive dysfunction, hippocampal atrophy …

Relationship between the plasma levels of neurodegenerative proteins and motor subtypes of Parkinson's disease

J Ding, J Zhang, X Wang, L Zhang, S Jiang… - Journal of neural …, 2017 - Springer
The aim of our study is to examine the plasma levels of the four kinds of neurodegenerative
proteins in plasma: α-syn, T-tau, P-tau 181, and Aβ-42 in Parkinson's disease (PD) and to …

[HTML][HTML] A multivariate predictive modeling approach reveals a novel CSF peptide signature for both Alzheimer's Disease state classification and for predicting future …

DA Llano, S Bundela, RA Mudar, V Devanarayan… - PloS one, 2017 - journals.plos.org
To determine if a multi-analyte cerebrospinal fluid (CSF) peptide signature can be used to
differentiate Alzheimer's Disease (AD) and normal aged controls (NL), and to determine if …

Resilience to Alzheimer's disease: the role of physical activity

A Pedrinolla, F Schena… - Current Alzheimer …, 2017 - ingentaconnect.com
Background: Although Alzheimer's disease (AD) is a neurodegenerative pathology
characterized by accumulation of β-amyloid plaques and neurofibrillary tangles at cerebral …

[HTML][HTML] Protein signature in cerebrospinal fluid and serum of Alzheimer's disease patients: The case of apolipoprotein A-1 proteoforms

C Fania, B Arosio, D Capitanio, E Torretta, C Gussago… - PloS one, 2017 - journals.plos.org
In the diagnosis of Alzheimer's disease (AD) total tau (T-tau), tau phosphorylated at
threonine 181 (P-tau181), and the 42 amino acid isoform of alpha β-amyloid (Aβ) are well …

Stress and its impact on cognition in mild cognitive impairment

R Sussams - 2017 - eprints.soton.ac.uk
Participants with amnestic Mild Cognitive Impairment (aMCI) do not inevitably show
cognitive decline or convert to Alzheimer's disease (AD) supporting the hypothesis that …