Aims Terms used in the field of chronic pelvic pain (CPP) are poorly defined and often
confusing. An International Continence Society (ICS) Standard for Terminology in chronic …

Bladder pain syndrome (BPS) is associated with breakdown of the protective uroepithelial
barrier of the urinary bladder allowing urinary constituents access to bladder sensory …

Интерстициальный цистит/Синдром болезненного мочевого пузыря является тяжелым
заболеванием с выраженным влиянием на качество жизни. Существующие методы …

Our goal was to evaluate the pain response in an LL-37 induced murine model for interstitial
cystitis/painful bladder syndrome (IC/PBS). In particular, we sought to characterize the dose …

US9789115B2 - Use of sigma ligands in opioid-induced hyperalgesia - Google Patents
US9789115B2 - Use of sigma ligands in opioid-induced hyperalgesia - Google Patents Use of …

US9844516B2 - Sigma ligands for use in the prevention and/or treatment of post-operative pain
- Google Patents US9844516B2 - Sigma ligands for use in the prevention and/or treatment of …

US9782483B2 - Sigma ligands for the prevention and/or treatment of emesis induced by
chemotherapy or radiotherapy - Google Patents US9782483B2 - Sigma ligands for the …

The present in vitro study investigated the influence of doxazosin on the contractility of the
urinary bladder in female pigs with experimentally induced cystitis. Fifteen juvenile female …

The invention refers to the use of a sigma ligand, particularly a sigma ligand of formula (I) to
prevent and/or treat type-2 diabetes-associated pain and related symptoms.(51) Int. Ci …

The invention refers to a combination comprising a sigma ligand of formula (I) and an opioid
or opiate for use in the prevention and/or treatment of pain developed as a consequence of …