Post-transcriptional regulation of cytokine and growth factor signaling in cancer

IVS Louis, PR Bohjanen - Cytokine & growth factor reviews, 2017 - Elsevier
Cytokines and growth factors regulate cell proliferation, differentiation, migration and
apoptosis, and play important roles in coordinating growth signal responses during …

Emerging role of HuR in inflammatory response in kidney diseases

J Shang, Z Zhao - Acta Biochimica et Biophysica Sinica, 2017 - academic.oup.com
Human antigen R (HuR) is a member of the embryonic lethal abnormal vision (ELAV) family
which can bind to the A/U rich elements in 3'un-translated region of mRNA and regulate …

Regulation of HuR structure and function by dihydrotanshinone-I

P Lal, L Cerofolini, VG D'Agostino, C Zucal… - Nucleic acids …, 2017 - academic.oup.com
The Human antigen R protein (HuR) is an RNA-binding protein that recognizes U/AU-rich
elements in diverse RNAs through two RNA-recognition motifs, RRM1 and RRM2, and post …

HuR enhances early restitution of the intestinal epithelium by increasing Cdc42 translation

L Liu, R Zhuang, L Xiao, HK Chung, J Luo… - … and Cellular Biology, 2017 - Am Soc Microbiol
The mammalian intestinal mucosa exhibits a spectrum of responses after acute injury and
repairs itself rapidly to restore the epithelial integrity. The RNA-binding protein HuR …

Repression of caspase-3 and RNA-binding protein HuR cleavage by cyclooxygenase-2 promotes drug resistance in oral squamous cell carcinoma

H Janakiraman, RP House, S Talwar, SM Courtney… - Oncogene, 2017 - nature.com
A well-studied RNA-binding protein Hu Antigen-R (HuR), controls post-transcriptional gene
regulation and undergoes stress-activated caspase-3 dependent cleavage in cancer cells …

Posttranscriptional regulation of cytokine expression

P Kovarik, F Ebner, V Sedlyarov - Cytokine, 2017 - Elsevier
Expression of cytokines and chemokines is regulated at multiple steps during the transfer of
the genetic information from DNA sequence to the functional protein. The multilayered …

[HTML][HTML] The RNA-binding protein HuR posttranscriptionally regulates IL-2 homeostasis and CD4+ Th2 differentiation

P Techasintana, JS Ellis, J Glascock, MM Gubin… - …, 2017 - journals.aai.org
Posttranscriptional gene regulation by RNA-binding proteins, such as HuR (elavl1), fine-
tune gene expression in T cells, leading to powerful effects on immune responses. HuR can …

Cell cycle RNA regulons coordinating early lymphocyte development

A Galloway, M Turner - Wiley Interdisciplinary Reviews: RNA, 2017 - Wiley Online Library
Lymphocytes undergo dynamic changes in gene expression as they develop from
progenitor cells lacking antigen receptors, to mature cells that are prepared to mount …

[HTML][HTML] RNA-binding proteins in female reproductive pathologies

K Khalaj, JE Miller, CR Fenn, SH Ahn, RL Luna… - The American journal of …, 2017 - Elsevier
RNA-binding proteins are key regulatory molecules involved primarily in post-transcriptional
gene regulation of RNAs. Post-transcriptional gene regulation is critical for adequate cellular …

Analysis of post-transcriptional regulation during cancer progression using a donor-derived isogenic model of tumorigenesis

LS Bisogno, JD Keene - Methods, 2017 - Elsevier
Post-transcriptional regulation of gene expression by RNA binding proteins (RBPs) and non-
coding RNAs plays an important role in global gene expression. Many post-transcriptional …