Hydrogen peroxide emerged as major redox metabolite operative in redox sensing,
signaling and redox regulation. Generation, transport and capture of H 2 O 2 in biological …

Estrogens and androgens influence the growth and maintenance of the mammalian
skeleton and are responsible for its sexual dimorphism. Estrogen deficiency at menopause …

This review is centered on the antioxidant enzyme catalase and will present different
aspects of this particular protein. Among them: historical discovery, biological functions …

Cancer cells are frequently confronted with metabolic stress in tumor microenvironments
due to their rapid growth and limited nutrient supply. Metabolic stress induces cell death …

The main forms of childhood malnutrition occur predominantly in children< 5 years of age
living in low-income and middle-income countries and include stunting, wasting and …

Age is the most important risk factor for most diseases. Mitochondria play a central role in
bioenergetics and metabolism. In addition, several lines of evidence indicate the impact of …

Oxidative stress is two sided: Whereas excessive oxidant challenge causes damage to
biomolecules, maintenance of a physiological level of oxidant challenge, termed oxidative …

Nowadays, it is known that oxidative stress plays at least two roles within the cell, the
generation of cellular damage and the involvement in several signaling pathways in its …

Antioxidant system loss after slaughtering, reactive species production, cell disruption,
contact with oxygen and light, heme and nonheme iron, and irradiation starts up mainly by 2 …

Sepsis is one of the main causes of death among critically ill patients. Sepsis pathogenesis
includes infection by gram-negative and gram-positive bacteria, fungi, or both; exacerbated …