It is well known that most brain disorders are complex diseases, such as Alzheimer's
disease (AD) and schizophrenia (SCZ). In general, brain regions and their interactions can …

Primary and persistent negative symptoms (PPNS) represent an unmet need in the care of
people with schizophrenia. They have an unfavourable impact on real-life functioning and …

White matter abnormalities associated with schizophrenia have been widely reported,
although the consistency of findings across studies is moderate. In this study, neuroimaging …

At the centenary of D'Arcy Thompson's seminal work 'On Growth and Form', pioneering the
description of principles of morphological changes during development and evolution …

Despite convergent evidence indicating a variety of regional abnormalities of hemispheric
asymmetry in schizophrenia, patterns of wider neural network asymmetry remain to be …

Background The dysconnectivity hypothesis suggests that psychotic illnesses arise not from
regionally specific focal pathophysiology, but rather from impaired neuroanatomical …

Most major psychiatric disorders arise from disturbances of anatomically distributed neural
systems rather than isolated dysfunction of circumscribed brain regions. The past decade …

Connectomic approaches using diffusion tensor imaging have contributed to our
understanding of brain changes in psychosis, and could provide further insights into the …

Schizophrenia is a disease with disruptions in thought, emotion, and behavior. The
dysconnectivity hypothesis suggests these disruptions are due to aberrant brain …

Parkinson's disease (PD) is considered as a neurodegenerative disorder of the brain central
nervous system. But, to date, few studies adopted the network model to reveal topological …