Rationale: Although not fully understood, the phenotypic transition of vascular smooth
muscle cells exhibits at the early onset of the pathology of aortic aneurysms. Exploring the …

Vascular mural cells (vMCs) are essential components of the vertebrate vascular system,
controlling blood vessel maturation and homeostasis. Discrete molecular mechanisms have …

Endothelial dysfunction is widely implicated in cardiovascular pathological changes and
development of vascular disease. In view of the fact that the spontaneous endothelial cell …

Vascular alterations are expected to occur in obese individuals but the impact of obesity
could be different depending on the artery type. We aimed to evaluate the obesity effects on …

Benzo [a] pyrene, a ubiquitous environmental pollutant, has been suggested to be capable
of initiating and/or accelerating atherosclerosis. Accumulation of vascular smooth muscle …

LIM domain proteins have been identified as essential modulators of cardiac biology and
pathology; however, it is unclear which role the cysteine‐rich LIM‐only protein (CRP) 4 plays …

Zhang and Xu Vascular Progenitors 247 mouse models. 10 It is therefore possible that
adventitial stem cells could be direct contributors to SMC accumulation in arteriosclerosis …

Highlights•Endothelial cells can be efficiently derived from human pluripotent stem
cells.•Current approaches to study network assembly use adult stem and mature …

The aim of vascular tissue engineering (VTE) is to fabricate tissues that are both
mechanically and biologically competent similar to the native vessel they are intended to …

Congenital heart disease represents the most common form of birth defect and is present in
up to 1% of all live births. Of particular interest to our group is the treatment of single ventricle …