The schizophrenia risk gene ZNF804A: clinical associations, biological mechanisms and neuronal functions
H Chang, X Xiao, M Li - Molecular psychiatry, 2017 - nature.com
ZNF804A (zinc-finger protein 804A) has been recognized as a schizophrenia risk gene
across multiple world populations. Its intronic single-nucleotide polymorphism (SNP) …
across multiple world populations. Its intronic single-nucleotide polymorphism (SNP) …
Molecular mechanisms underlying noncoding risk variations in psychiatric genetic studies
Recent large-scale genetic approaches such as genome-wide association studies have
allowed the identification of common genetic variations that contribute to risk architectures of …
allowed the identification of common genetic variations that contribute to risk architectures of …
[HTML][HTML] Psychosis risk candidate ZNF804A localizes to synapses and regulates neurite formation and dendritic spine structure
Background Variation in the gene encoding zinc finger binding protein 804A (ZNF804A) is
associated with schizophrenia and bipolar disorder. Evidence suggests that ZNF804A is a …
associated with schizophrenia and bipolar disorder. Evidence suggests that ZNF804A is a …
Genetics of psychosis of Alzheimer disease
C Shah, MAA DeMichele‐Sweet… - American Journal of …, 2017 - Wiley Online Library
Psychotic symptoms, comprised of delusions and hallucinations, occur in about half of
individuals with Alzheimer disease (AD with psychosis, AD+ P). These individuals have …
individuals with Alzheimer disease (AD with psychosis, AD+ P). These individuals have …
The genome-wide associated candidate gene ZNF804A and psychosis-proneness: Evidence of sex-modulated association
M de Castro-Catala, A Mora-Solano, TR Kwapil… - PLoS …, 2017 - journals.plos.org
Background The Zinc finger protein 804A (ZNF804A) is a promising candidate gene for
schizophrenia and the broader psychosis phenotype that emerged from genome-wide …
schizophrenia and the broader psychosis phenotype that emerged from genome-wide …
The schizophrenia susceptibility gene ZNF804A confers risk of major mood disorders
J Ou, M Li, X Xiao - The World Journal of Biological Psychiatry, 2017 - Taylor & Francis
Objectives: Genome-wide association studies (GWAS) followed by independent replications
suggest that ZNF804A is a risk gene for schizophrenia (SCZ), considering the substantial …
suggest that ZNF804A is a risk gene for schizophrenia (SCZ), considering the substantial …
Analyzing a single nucleotide polymorphism in schizophrenia: a meta-analysis approach
Background Schizophrenia is a severe mental disorder affecting> 21 million people
worldwide. Some genetic studies reported that single nucleotide polymorphism (SNP) …
worldwide. Some genetic studies reported that single nucleotide polymorphism (SNP) …
Genetic association of rs1344706 in ZNF804A with bipolar disorder and schizophrenia susceptibility in Chinese populations
Rs1344706 in the the zinc finger protein 804A (ZNF804A) gene has been identified to be
associated with schizophrenia and bipolar disorder (BD) in Europeans. However, whether …
associated with schizophrenia and bipolar disorder (BD) in Europeans. However, whether …
Association between the zinc finger protein 804A (ZNF804A) gene and the risk of schizophrenia and bipolar I disorder across diagnostic boundaries
Objectives In this study, we aimed to determine the role of genetic variations within the zinc
finger protein 804A (ZNF 804A) gene, a candidate for a psychosis risk‐conferring gene, in …
finger protein 804A (ZNF 804A) gene, a candidate for a psychosis risk‐conferring gene, in …
Znf804a 基因在发育期鼠脑神经元的迁移, 增殖及分化中的功能.
陈天达， 吴秦伟， 卢天兰， 岳伟华… - Chinese Mental Health …, 2017 - search.ebscohost.com
目的: 以小鼠为模型研究精神分裂症易感基因Znf804a 在神经发育中的功能. 方法:
利用胚胎电转技术, 将Znf804a 的shRNA (shZnf804a) 质粒及其对照质粒(pSUPER) …
利用胚胎电转技术, 将Znf804a 的shRNA (shZnf804a) 质粒及其对照质粒(pSUPER) …