Three‑dimensional cell culture: A powerful tool in tumor research and drug discovery

D Lv, Z Hu, L Lu, H Lu, X Xu - Oncology letters, 2017 - spandidos-publications.com
In previous years, three‑dimensional (3D) cell culture technology has become a focus of
research in tumor cell biology, using a variety of methods and materials to mimic the in vivo …

Three‐dimensional cell culture model utilization in cancer stem cell research

ZF Bielecka, K Maliszewska‐Olejniczak… - Biological …, 2017 - Wiley Online Library
ABSTRACT Three‐dimensional (3D) cell culture models are becoming increasingly popular
in contemporary cancer research and drug resistance studies. Recently, scientists have …

Electrospinning PCL scaffolds manufacture for three-dimensional breast cancer cell culture

M Rabionet, M Yeste, T Puig, J Ciurana - Polymers, 2017 - mdpi.com
In vitro cell culture is traditionally performed within two-dimensional (2D) environments,
providing a quick and cheap way to study cell properties in a laboratory. However, 2D …

PEG‐fibrinogen hydrogels for three‐dimensional breast cancer cell culture

S Pradhan, I Hassani, WJ Seeto… - Journal of Biomedical …, 2017 - Wiley Online Library
Abstract Tissue‐engineered three‐dimensional (3D) cancer models employing biomimetic
hydrogels as cellular scaffolds provide contextual in vitro recapitulation of the native tumor …

Growth of MCF-7 breast cancer cells and efficacy of anti-angiogenic agents in a hydroxyethyl chitosan/glycidyl methacrylate hydrogel

H Wang, J Qian, Y Zhang, W Xu, J Xiao, A Suo - Cancer Cell International, 2017 - Springer
Background Breast cancer negatively affects women's health worldwide. The tumour
microenvironment plays a critical role in tumour initiation, proliferation, and metastasis …

Nanofibrous matrixes with biologically active hydroxybenzophenazine pyrazolone compound for cancer theranostics

S Kandhasamy, G Ramanathan, T Muthukumar… - Materials Science and …, 2017 - Elsevier
The nanomaterial with the novel biologically active compounds has been actively
investigated for application in cancer research. Substantial use of nanofibrous scaffold for …

Electrospinning parameters selection to manufacture polycaprolactone scaffolds for three-dimensional breast cancer cell culture and enrichment

M Rabionet, T Puig, J Ciurana - Procedia CIRP, 2017 - Elsevier
Only a small cell population of a breast tumour presents stem cell characteristics, thus so-
called breast cancer stem cells (BCSCs). BCSCs are tumour-initiating cells and …

[HTML][HTML] 殼聚醣奈米纖維接枝玻尿酸以擴增並提高癌症幹細胞的比例

ZJ Hong - 2017 - ir.lib.ncu.edu.tw
摘要(中) 殼聚醣是常用的支架材料, 具有促進癌症細胞群聚成球狀並提升幹細胞的特性.
為了可以模擬體內的微環境, 因此我們利用電紡絲技術製備出殼聚醣奈米纖維絲 …

Bioengineered 3D scaffolds in cancer research: Focus on epithelial to mesenchymal transition and drug screening

X Xu, LL Tang - Current Pharmaceutical Design, 2017 - ingentaconnect.com
Background: The living environment of cancer cells is complicated and information-rich.
Thus, traditional 2D culture mold in vitro cannot mimic the microenvironment of cancer cells …

Electrospinning PCL Scaffolds Manufacture for Three-Dimensional Breast Cancer Cell Culture

M Rabionet Díaz, M Yeste Oliveras… - … vol. 9, núm. 8, p. 328, 2017 - dugi-doc.udg.edu
In vitro cell culture is traditionally performed within two-dimensional (2D) environments,
providing a quick and cheap way to study cell properties in a laboratory. However, 2D …