Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial …

P Toth, S Tarantini, A Csiszar… - American Journal of …, 2017 - journals.physiology.org
Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease

A Csiszar, S Tarantini, GA Fülöp, T Kiss… - Geroscience, 2017 - Springer
Hypertension in the elderly substantially increases both the risk of vascular cognitive
impairment (VCI) and Alzheimer's disease (AD); however, the underlying mechanisms are …

Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of …

Z Tucsek, M Noa Valcarcel-Ares, S Tarantini… - Geroscience, 2017 - Springer
Strong epidemiological and experimental evidence indicates that hypertension has
detrimental effects on the cerebral microcirculation and thereby promotes accelerated brain …

Arab American cognitive aging: Opportunities for advancing research on Alzheimer's disease disparities

KJ Ajrouch, LB Zahodne, TC Antonucci - Innovation in Aging, 2017 - academic.oup.com
Abstract Background and Objectives This article highlights the dearth of and need for
research on Arab American cognitive aging. We propose that studying cognitive health …

[HTML][HTML] A Bayesian model for the prediction and early diagnosis of Alzheimer's disease

A Alexiou, VD Mantzavinos, NH Greig… - Frontiers in aging …, 2017 - frontiersin.org
Alzheimer's disease treatment is still an open problem. The diversity of symptoms, the
alterations in common pathophysiology, the existence of asymptomatic cases, the different …

[PDF][PDF] Indapamide suppresses amyloid-β production in cellular models of Alzheimer's disease through regulating BACE1 activity

M Lu, L Ma, X Wang, W Jiang, P Shan - Int J Clin Exp Med, 2017 - e-century.us
Amyloid-β (Aβ) peptide is present in high levels in the brains of Alzheimer's disease (AD)
patients and is closely associated with the pathogenesis of the disease. In the present study …

Tongxinluo improves cognition by decreasing β-amyloid in spontaneous hypertensive rats

YL Fei, HJ Lv, YB Li, J Liu, YH Qian, WN Yang, KG Ma… - Brain Research, 2017 - Elsevier
Abstract β-Amyloid (Aβ) accumulation in the brain is the major pathophysiology of Alzheimer
disease (AD). Hypertension is a risk factor for AD by promoting Aβ deposition. Traditional …

[HTML][HTML] Advances in cardiovascular geroscience: functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral …

P Toth, S Tarantini, A Csiszar… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …

[引用][C] 以潛在類別模式分析臺灣老年人失智之相關因素

邱嵩斌 - 2017 - 國立台北護理健康大學健康事業管理 …