Cancer cells can inhibit effector T cells (Teff) through both immunomodulatory receptors and
the impact of cancer metabolism on the tumor microenvironment. Indeed, Teff require high …

Alzheimer's disease (AD) is progressive neurodegenerative disorder characterized by
accumulation of senile plaques, neurofibrillary tangles (NFT) and neurodegeneration. The …

Insulin, downstream of Akt activation, promotes glucose uptake into fat and muscle cells to
lower postprandial blood glucose, an enforced change in cellular metabolism to maintain …

Intracellular pathogens have evolved mechanisms to ensure their survival and development
inside their host cells. Here, we show that glucose is a pivotal modulator of hepatic infection …

Motivation Genome-wide association studies are identifying single nucleotide variants
(SNVs) linked to various diseases, however the functional effect caused by these variants is …

Excitatory amino acid transporters (EAATs) expressed in astrocytes remove the glutamate
released by neurons in and around the synaptic cleft. In this manner, astrocytes preserve the …

Insulin, downstream of Akt activation, promotes glucose uptake into fat and muscle cells to
lower postprandial blood glucose, an enforced change in cellular metabolism to maintain …

Despite having the same" purpose", the uncontrollable cellular growth to the detriment of the
organism, cancer presents itself in humans in great variety of forms. This variety makes …