The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

Nitrogen-containing heterocyclic compounds and their derivatives have historically been
invaluable as a source of therapeutic agents. Pyrazole, which has two nitrogen atoms and …

Dipolar cycloaddition of diazo compounds with olefinic substrates is a promising atom‐
economic strategy for the construction of functionalized pyrazoles. Over the last few years …

Molecules containing a nitrogen–nitrogen (N–N) linkage have a variety of structures and
biological activities; however, no enzyme has yet been demonstrated to catalyze N–N bond …

A variety of spirocyclohexene pyrazolones were synthesized in good yields with excellent
stereoselectivities through an asymmetric, intermolecular, quaternary carbon center forming …

An unprecedented highly regio‐and enantioselective rhodium‐catalyzed addition of 1, 3‐
diketones to terminal and 1, 1‐disubstituted allenes furnishing asymmetric tertiary and …

A new series of N-Boc ketimines derived from pyrazolin-5-ones have been used as
electrophiles in asymmetric Mannich reactions with pyrazolones. The amino-bis-pyrazolone …

Enantioselective synthesis of pyrazolone-fused spirocyclohexenols by the secondary amine-
catalyzed cascade reaction of α, β-unsaturated aldehydes with α-arylidene pyrazolinones is …

Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: an efficient
strategy for the synthesis of substituted 1-tosyl-1 H -p ... - Chemical Communications (RSC …

Oxidative-stress induces inflammatory diseases and infections caused by drug-resistant
microbial strains are on the rise necessitating the discovery of novel small-molecules for …