[PDF][PDF] Genome regulation by polycomb and trithorax: 70 years and counting
B Schuettengruber, HM Bourbon, L Di Croce, G Cavalli - Cell, 2017 - cell.com
Polycomb (PcG) and Trithorax (TrxG) group proteins are evolutionarily conserved chromatin-
modifying factors originally identified as part of an epigenetic cellular memory system that …
modifying factors originally identified as part of an epigenetic cellular memory system that …
Compositional and functional diversity of canonical PRC1 complexes in mammals
KE Connelly, EC Dykhuizen - Biochimica et Biophysica Acta (BBA)-Gene …, 2017 - Elsevier
The compositional complexity of Polycomb Repressive Complex 1 (PRC1) increased
dramatically during vertebrate evolution. What is considered the “canonical” PRC1 complex …
dramatically during vertebrate evolution. What is considered the “canonical” PRC1 complex …
[HTML][HTML] CBX7 suppresses cell proliferation, migration, and invasion through the inhibition of PTEN/Akt signaling in pancreatic cancer
S Ni, H Wang, X Zhu, C Wan, J Xu, C Lu, L Xiao, J He… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Chromobox protein homolog 7 (CBX7), one of the polycomb group (PcG) proteins,
is a transcriptional repressor involved in the regulation of cell proliferation and senescence …
is a transcriptional repressor involved in the regulation of cell proliferation and senescence …
Identification of BMI1 Promoter Inhibitors from Beaumontia murtonii and Eugenia operculata
B-Cell-specific Moloney murine leukemia virus insertion region 1 (BMI1) is a core
component of the polycomb repressive complex 1 (PRC1). Abnormal expression of BMI1 is …
component of the polycomb repressive complex 1 (PRC1). Abnormal expression of BMI1 is …
[HTML][HTML] High BMI1 mRNA expression in peripheral whole blood is associated with favorable prognosis in advanced non-small cell lung cancer patients
Polycomb group member protein BMI1 is involved in maintaining cell identity, proliferation,
differentiation and human oncogenesis. In the present study, we determined BMI1 mRNA …
differentiation and human oncogenesis. In the present study, we determined BMI1 mRNA …
[HTML][HTML] Participation of BMI-1 protein in cancer
A Zaczek, P Jóźwiak, A Krześlak - Advances in Hygiene and Experimental …, 2017 - phmd.pl
BMI-1 (B-lymphoma Mo-MLV insertion region 1) protein is a constituent of Polycomb
Repressive Complex 1 (PRC1) that via ubiquitination of histone H2A affects expression of …
Repressive Complex 1 (PRC1) that via ubiquitination of histone H2A affects expression of …
Prognostic significance of BMI-1 but not MEL-18 expression in pulmonary squamous cell carcinoma
S Abe, SI Yamashita, SO Miyahara… - Anticancer …, 2017 - ar.iiarjournals.org
Aim: We investigated the possibility of BMI-1 and MEL-18 to predict survival in patients with
pulmonary squamous cell carcinoma. Materials and Methods: One hundred and ninety-nine …
pulmonary squamous cell carcinoma. Materials and Methods: One hundred and ninety-nine …
Expression and clinicopathological significance of Mel-18 and Bmi-1 in esophageal squamous cell carcinoma
H Ji, M Cao, K Ren, N Sun, W Wang… - … in Cancer Research …, 2017 - journals.sagepub.com
The Polycomb group genes are a general class of regulators that are responsible for
maintaining homeotic gene expression throughout cell division. Polycomb group expression …
maintaining homeotic gene expression throughout cell division. Polycomb group expression …
[HTML][HTML] 蓬子菜总黄酮诱导NB4 细胞凋亡作用及机制
朱玉良， 马英丽， 李瑞， 张紫阳， 董均明， 马玲 - 中国公共卫生, 2017 - html.rhhz.net
目的观察蓬子菜总黄酮(FGVL) 诱导急性早幼粒细胞白血病细胞株(NB4) 细胞凋亡作用,
并探讨其作用机制. 方法FGVL (50,100,200 μg/mL) 作用于体外培养的NB4 细胞, Hoechst …
并探讨其作用机制. 方法FGVL (50,100,200 μg/mL) 作用于体外培养的NB4 细胞, Hoechst …
[PDF][PDF] Bmi1–A Path to Targeting Cancer Stem Cells
D Bakhshinyan, AA Adile, C Venugopal… - Journal-Bmi1–A Path …, 2017 - researchgate.net
The Polycomb group (PcG) genes encode for proteins comprising two multiprotein
complexes, Polycomb repressive complex 1 (PRC1) and Polycomb repressive complex 2 …
complexes, Polycomb repressive complex 1 (PRC1) and Polycomb repressive complex 2 …