Introduction: Procalcitonin is a surrogate infection blood marker whose levels help estimate
the likelihood of bacterial infections and correlate with their resolution. Recent trials have …

Sepsis remains a highly lethal entity resulting in more than 200 000 deaths in the USA each
year. The in-hospital mortality approaches 30% despite advances in critical care during the …

Background Delayed pathogen identification and nonspecific clinical findings make
definitive decisions regarding antibiotics challenging. The stimuli of bacterial toxins and …

Sepsis is a clinical syndrome that has physiologic, biologic, and biochemical abnormalities
caused by a dysregulated host response to infection. Sepsis and the inflammatory response …

Laboratory medicine and clinical medicine are co-dependent components of medicine.
Laboratory medicine functions most effectively when focused through a clinical lens. Me …

Zusammenfassung Die Sterblichkeit von Patienten mit Sepsis und septischem Schock ist
weiterhin inakzeptabel hoch. Eine effektive, kalkulierte Antibiotikatherapie binnen der ersten …

Background: Several trials found procalcitonin (PCT) helpful for guiding antibiotic treatment
in patients with lower respiratory tract infections and sepsis. We aimed to perform an …

Due to overlap of clinical findings and low sensitivity of bacterial diagnostic tests,
differentiation between bacterial and viral respiratory tract infections remains challenging …

We considered extremely relevant the prospective, mul-ticenter MOnitoring SEpsis Study
(MOSES) conducted by Schuetz et al (1), in a recent issue of Critical Care Medicine …

The article discusses the clinical practice guidelines and diagnostic solutions aimed at
sepsis. Topics covered include the inverse relationship between time to optimal treatment …