Over 100 million women worldwide are currently on progesterone-based contraceptives to
improve their health outcomes through reduced maternal mortality and family planning. In …

The Global Plan towards the elimination of new HIV infections among children by 2015 and
keeping their mothers alive (Global Plan) has ensured that more infants in high-HIV burden …

Background. Globally, family planning services are being strengthened and the range of
contraceptive choices expanded. Data on contraceptive coverage and service gaps could …

Zika virus (ZIKV) is a mosquito-transmitted virus that can cause severe defects in an infected
fetus. ZIKV is also transmitted by sexual contact, although the relative importance of sexual …

Background. Increasing evidence suggests depot medroxyprogesterone acetate (DMPA)
and intravaginal practices may be associated with human immunodeficiency virus (HIV-1) …

Understanding early events of HIV transmission within mucosal tissues is vital for
developing effective prevention strategies. Here, we report that primary stromal fibroblasts …

The human immunodeficiency virus (HIV)-1 epidemic continues to represent a global health
problem that is over-proportionally affecting women from sub-Saharan Africa. Besides social …

Background: In vitro, animal, biological and observational clinical studies suggest that some
hormonal methods, particularly depot medroxyprogesterone acetate–DMPA, may increase …

The most immediate and evident effect of mucosal exposure to semen in vivo is a local
release of proinflammatory mediators accompanied by an influx of leukocytes into the …

Interferon epsilon (IFNɛ) is a type I IFN that is expressed constitutively in the female
reproductive tract (FRT), and contributes to protection in models of sexually transmitted …