Recent epidemiological evidence reveals that patients suffering from type 2 diabetes
mellitus (T2DM) often experience a significant decline in cognitive function, and …

In many of the neurodegenerative diseases, such as Alzheimer's disease (AD) and AD-
related disorders, as well as in the regular ageing process, excessive generation of …

Mutations in amyloid β precursor protein (APP) gene alter APP processing, either causing
familial Alzheimer9s disease (AD) or protecting against dementia. Under normal conditions …

Deposition of amyloid β protein (Aβ) to form neuritic plaques in the brain is the unique
pathological hallmark of Alzheimer's disease (AD). Aβ is derived from amyloid β precursor …

Alzheimer's disease (AD) is a chronic neurodegenerative disease leading to dementia,
which is characterized by progressive memory loss and other cognitive dysfunctions. Recent …

One of the pathogenic systems of Alzheimer's disease (AD) is the formation of β‐amyloid
plaques in the brains of patients, and amyloidogenic activity becomes one of the therapeutic …

Accumulation of amyloid β protein (Aβ)-containing neuritic plaques in the brain is a
neuropathological feature of Alzheimer's disease (AD). The β-site APP-cleaving enzyme 1 …

Background: Although clinical vitamin A deficiency (VAD), which is a public health problem
developing throughout the world, has been well controlled, marginal vitamin A deficiency …

The cis/trans isomerization of X-Pro peptide bonds in proteins in some instances acts as a
molecular switch in biological pathways. Our prior work suggests that the cis isomer of the …

Alzheimer's disease (AD) and Parkinson's disease (PD) are featured by cholinergic and
dopaminergic neuron loss, respectively. As a unique pathological hallmark of AD, neuritic …