Primary Sjögren's syndrome: clinical phenotypes, outcome and the development of biomarkers
AV Goules, AG Tzioufas - Immunologic research, 2017 - Springer
Primary Sjögren's syndrome is a complex, autoimmune disease with distinct clinical
phenotypes and variable outcomes. The systemic form of the disease is characterized by …
phenotypes and variable outcomes. The systemic form of the disease is characterized by …
Upregulation of Flt3 is a passive event in Hoxa9/Meis1-induced acute myeloid leukemia in mice
A Staffas, LS Arabanian, SY Wei, A Jansson… - Oncogene, 2017 - nature.com
Abstract HOXA9, MEIS1 and FLT3 are genes frequently upregulated in human acute
myeloid leukemia. Hoxa9 and Meis1 also cooperate to induce aggressive AML with high …
myeloid leukemia. Hoxa9 and Meis1 also cooperate to induce aggressive AML with high …
TGFβ1 synergizes with FLT3 ligand to induce chemoresistant quiescence in acute lymphoblastic leukemia with MLL gene rearrangements.
M Tamai, Y Furuichi, S Kasai, N Ando, D Harama… - Leukemia Research, 2017 - Elsevier
Fms-like tyrosine kinase 3 (FLT3) is highly expressed in mixed-lineage leukemia (MLL)
gene-rearranged acute lymphoblastic leukemia (MLL+ ALL) with a dismal prognosis. We …
gene-rearranged acute lymphoblastic leukemia (MLL+ ALL) with a dismal prognosis. We …
Serum levels of soluble FLT3 ligand in patients with active multiple myeloma constitute marker of bone marrow plasma cell proliferative activity
M Kokonozaki, P Kanellou, CA Pappa… - Critical Reviews™ in …, 2017 - dl.begellhouse.com
The FLT3-ligand is a molecule implicated in hematopoiesis. The aim of the present study
was to detect any possible connections between serum levels of FLT3-L and multiple …
was to detect any possible connections between serum levels of FLT3-L and multiple …
Flt3 ligand‐eGFP‐reporter expression characterizes functionally distinct subpopulations of CD150+ long‐term repopulating murine hematopoietic stem cells
J Tornack, Y Kawano, N Garbi… - European Journal of …, 2017 - Wiley Online Library
The pool of hematopoietic stem cells (HSCs) in the bone marrow is a mixture of resting,
proliferating, and differentiating cells. Long‐term repopulating HSCs (LT‐HSC) are routinely …
proliferating, and differentiating cells. Long‐term repopulating HSCs (LT‐HSC) are routinely …
Microenvironnement médullaire et résistance des LAM FLT3-ITD aux inhibiteurs de tyrosine kinase: Rôle pivot du récepteur TAM AXL
PY Dumas - 2017 - theses.hal.science
La duplication interne en tandem au sein du gène du Fms-like tyrosine kinase 3 (FLT3) est
l'une des mutations les plus fréquemment observées dans les leucémies aiguës …
l'une des mutations les plus fréquemment observées dans les leucémies aiguës …
Rôle des cellules dendritiques plasmocytoïdes dans la leucémie myélomonocytaire chronique
N Lucas - 2017 - theses.hal.science
Une infiltration médullaire par des cellules plasmocytoïdes CD123+ est présente chez
certains patients atteints de leucémie myélomonocytaire chronique (LMMC), mais les …
certains patients atteints de leucémie myélomonocytaire chronique (LMMC), mais les …