Natural products that contain functional groups with heteroatom-heteroatom linkages (X–X,
where X= N, O, S, and P) are a small yet intriguing group of metabolites. The reactivity and …

Nowadays, hybrid drugs containing two or more covalently linked known potential
pharmacophores are designed to simultaneously modulate multiple targets of multifactorial …

Cheap and commercially available trichloroisocyanuric acid has been used to promote
trifluoromethylation by using TMSCF3 as the trifluoromethyl source. The method provides a …

DFT calculations were performed to shed light on the molecular mechanism of [3+ 2]
cycloadditions of simple conjugated nitroalkenes to benzonitrile N-oxides. In particular, it …

Mental disorders are neuropsychiatric conditions that are marked by unusual or irregular
thinking, feelings, or behavior, and lead to distress and/or impaired functions. Major …

Abstract A Mo (CO) 6 (molybdenumhexacarbonyl) catalyzed reductive functionalization of
amides to afford 5‐amino substituted 4, 5‐dihydroisoxazoles is presented. The reduction of …

Abstract 12 novel scopoletin-isoxazole and scopoletin-pyrazole hybrids were designed,
synthesized and their chemical structures were confirmed by HR-MS, IR, 1 H NMR and 13 C …

Abstract A base‐promoted [3+ 2]‐annulation of ketoxime esters and aldehydes is disclosed
for the facile and rapid synthesis of 3, 5‐disubstituted and 3, 4, 5‐trisubstituted isoxazolines …

An environment benign process has been developed for the regioselective synthesis of 5-
iodo-1, 4-disubstituted-1, 2, 3-triazoles catalyzed by CuI/β-CD in water. Moreover, the …

A simple, general, and regioselective method has been developed for the synthesis of a
series of heteroarylfuroxans, including isoxazolyl-, isoxazolinyl-and (1, 2, 4-oxadiazolyl) …