Metabolomics, or the comprehensive profiling of small molecule metabolites in cells, tissues,
or whole organisms, has undergone a rapid technological evolution in the past two decades …

Chronic kidney disease (CKD) has a high prevalence in the general population and is
associated with high mortality; a need therefore exists for better biomarkers for diagnosis …

The active form of vitamin B6, pyridoxal 5′-phosphate (PLP), serves as a co-factor in more
than 150 enzymatic reactions. Plasma PLP has consistently been shown to be low in …

Wide-scale profiling technologies including metabolomics broaden the possibility of novel
discoveries related to the pathogenesis of type 2 diabetes (T2D). By applying non-targeted …

Abstract Introduction The Alzheimer's Disease Research Summits of 2012 and 2015
incorporated experts from academia, industry, and nonprofit organizations to develop new …

A critical question facing the field of metabolomics is whether data obtained from different
centers can be effectively compared and combined. An important aspect of this is the …

Background: Meat and fish intakes have been associated with various chronic diseases. The
use of specific biomarkers may help to assess meat and fish intake and improve subject …

Aims/hypothesis The aims of this study were to evaluate systematically the predictive power
of comprehensive metabolomics profiles in predicting the future risk of type 2 diabetes, and …

Abstract Type 2 diabetes (T2D) and cancers are two major causes of morbidity and mortality
worldwide. Nowadays, there is convincing evidence of positive associations between T2D …

Background The growing field of metabolomics has opened up new opportunities for
prediction of type 2 diabetes (T2D) going beyond the classical biochemistry assays …