[HTML][HTML] Hinokitiol up-regulates miR-494-3p to suppress BMI1 expression and inhibits self-renewal of breast cancer stem/progenitor cells

SM Chen, BY Wang, CH Lee, HT Lee, JJ Li, GC Hong… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Hinokitiol (β-thujaplicin) is a tropolone-related compound that has anti-microbe, anti-
inflammation, and anti-tumor effects. Cancer stem/progenitor cells (CSCs) are a …

Hsp90α mediates BMI1 expression in breast cancer stem/progenitor cells through facilitating nuclear translocation of c-Myc and EZH2

YC Lee, WW Chang, YY Chen, YH Tsai… - International Journal of …, 2017 - mdpi.com
Heat shock protein 90 (Hsp90) is a molecular chaperone that facilitates the correct folding
and functionality of its client protein. Numerous Hsp90-client proteins are involved in cancer …

[PDF][PDF] Circulating Bmi-1 mRNA as a diagnostic and prognostic biomarker for non-small cell lung cancer

QB Hou, CR Zhao, XY Wang, H Shi - Int J Clin Exp Path, 2017 - e-century.us
Bmi-1, a key member of the Polycomb group complex, has been shown in non-small cell
lung cancer (NSCLC) tumorigenesis and progress. The aim of this study was to detect the …

PRC1 Prevents Replication Stress during Chondrogenic Transit Amplification

F Spaapen, LMT Eijssen, ME Adriaens, TJ Welting… - Epigenomes, 2017 - mdpi.com
Transit amplification (TA), a state of combined, rapid proliferative expansion and
differentiation of stem cell-descendants, remains poorly defined at the molecular level. The …