[HTML][HTML] BDNF in the aged brain: translational implications for Parkinson's disease

NM Mercado, TJ Collier, CE Sortwell… - Austin neurology & …, 2017 - ncbi.nlm.nih.gov
Abstract Brain Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family
of secreted growth factors. BDNF signaling is known to exert both chronic, pro-survival …

Neurotrophin receptor signaling as a therapeutic target for Huntington's disease

DA Simmons, FM Longo… - CNS & Neurological …, 2017 - ingentaconnect.com
Effective non-genetic disease modifying treatments for Huntington's disease (HD) will
necessarily target multiple diverse neurodegenerative processes triggered by mutant …

Striatal neuropeptides enhance selection and rejection of sequential actions

D Buxton, E Bracci, PG Overton… - Frontiers in computational …, 2017 - frontiersin.org
The striatum is the primary input nucleus for the basal ganglia, and receives glutamatergic
afferents from the cortex. Under the hypothesis that basal ganglia perform action selection …

Ventricular fibrillation cardiac arrest produces a chronic striatal hyperdopaminergic state that is worsened by methylphenidate treatment

GJ Nora, R Harun, DF Fine, D Hutchison… - Journal of …, 2017 - Wiley Online Library
Cardiac arrest survival rates have improved with modern resuscitation techniques, but many
survivors experience impairments associated with hypoxic‐ischemic brain injury (HIBI) …

Changes in striatal activity and functional connectivity in a mouse model of Huntington's disease

M Cabanas, F Bassil, N Mons, M Garret, YH Cho - Plos one, 2017 - journals.plos.org
Hereditary Huntington's disease (HD) is associated with progressive motor, cognitive and
psychiatric symptoms. A primary consequence of the HD mutation is the preferential loss of …

Regulation of NMDA receptor surface distribution in a neuronal model of Huntington's disease

W Ambroziak - 2017 - researchspace.auckland.ac.nz
Huntington's disease (HD) is a neurodegenerative genetic disorder caused by an expansion
of the CAG repeat tract in the HTT gene, leading to a triad of motor, cognitive and psychiatric …

Neurobehavioral correlates of action control in an animal model of attention-deficit/hyperactivity disorder

JY Natsheh - 2017 - rucore.libraries.rutgers.edu
Attention-Deficit/Hyperactivity Disorder (ADHD) is typically diagnosed in childhood and can
continue to adolescence and adulthood. It is characterized by developmentally …