A woman has an increased risk of breast cancer if her lifelong estrogen exposure is
increased due to an early menarche, a late menopause, and/or an absence of childbearing …

Methods The PubMed database was searched using the following medical subject heading
terms and keywords: delayed puberty, adult height, BMD, fracture, depression, substance …

Background Despite evidence that genetic factors contribute to the duration of gestation and
the risk of preterm birth, robust associations with genetic variants have not been identified …

Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We
performed a genome-wide association study for whole body (20 cohorts of European …

BACKGROUND Puberty is a complex developmental event, controlled by sophisticated
regulatory networks that integrate peripheral and internal cues and impinge at the brain …

Puberty is a major developmental stage. Damaging mutations, considered as “mistakes of
nature”, have contributed to the unraveling of the networks implicated in the normal initiation …

Context Obesity in men is associated with low serum testosterone and both are associated
with several diseases and increased mortality. Objectives Examine the direction and …

Objective Early puberty in girls is linked to some adverse outcomes in adolescence and mid-
life. We address two research questions:(1) Are socioeconomic circumstances and ethnicity …

Objective: The aim of the present study was to investigate associations between
reproductive factors and survival to age 90 years. Methods: This was a prospective study of …

Male-pattern baldness (MPB) is a common and highly heritable trait characterized by
androgen-dependent, progressive hair loss from the scalp. Here, we carry out the largest …