Introduction: Adjuvants are used to improve vaccine immunogenicity and efficacy by
enhancing antigen presentation to antigen-specific immune cells with the aim to confer long …

Development of an efficacious HIV‐1 vaccine is a major priority for improving human health
worldwide. Vaccine‐mediated protection against human pathogens can be achieved …

RTS, S is an advanced malaria vaccine candidate and confers significant protection against
Plasmodium falciparum infection in humans. Little is known about the molecular …

Acquired resistance against antimalarial drugs has further increased the need for an
effective malaria vaccine. The current leading candidate, RTS, S, is a recombinant …

Although vaccines would be the ideal tool for control, prevention, elimination, and
eradication of many infectious diseases, developing of parasites vaccines such as malaria …

Several species of Plasmodium cause a broad spectrum of human disease that range from
nausea and fever to severe anemia, cerebral malaria, and multiorgan failure. In malaria …

Malaria caused by Plasmodium falciparum continues to threaten millions of people living in
the tropical parts of the world. A vaccine that confers sterile and life-long protection remains …

Recent studies have shown that immune responses against the cell-traversal protein for
Plasmodium ookinetes and sporozoites (CelTOS) can inhibit parasite infection. While these …

Vaccines represent one of the most successful chapters in the history of medicine. Over the
past decades, the advent of recombinant cDNA technology has enabled the biomedical …

Heterologous prime-boosting with viral vectors encoding the pre-erythrocytic antigen
thrombospondin-related adhesion protein fused to a multiple epitope string (ME-TRAP) …