Metabolomics: a primer

X Liu, JW Locasale - Trends in biochemical sciences, 2017 - cell.com
Metabolomics generates a profile of small molecules that are derived from cellular
metabolism and can directly reflect the outcome of complex networks of biochemical …

Understanding metabolism with flux analysis: From theory to application

Z Dai, JW Locasale - Metabolic engineering, 2017 - Elsevier
Quantitative and qualitative knowledge of metabolic rates (ie fluxes) over a metabolic
network and in specific cellular compartments gives insights into the regulation of …

Person re-identification by deep learning attribute-complementary information

A Schumann, R Stiefelhagen - Proceedings of the IEEE …, 2017 - openaccess.thecvf.com
Automatic person re-identification (re-id) across camera boundaries is a challenging
problem. Approaches have to be robust against many factors which influence the visual …

[HTML][HTML] Use of CellNetAnalyzer in biotechnology and metabolic engineering

A von Kamp, S Thiele, O Hädicke, S Klamt - Journal of biotechnology, 2017 - Elsevier
Mathematical models of the cellular metabolism have become an essential tool for the
optimization of biotechnological processes. They help to obtain a systemic understanding of …

Recent advances in high-throughput 13C-fluxomics

S Heux, C Bergès, P Millard, JC Portais… - Current opinion in …, 2017 - Elsevier
Highlights•13 C-fluxomics provides quantification of metabolic activity in microorganisms.•
Increasing flux analysis capacity has the potential to accelerate strain design.•HT 13 C …

Exo-MFA–a 13C metabolic flux analysis framework to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism

A Achreja, H Zhao, L Yang, TH Yun, J Marini… - Metabolic …, 2017 - Elsevier
Dissecting the pleiotropic roles of tumor micro-environment (TME) on cancer progression
has been brought to the foreground of research on cancer pathology. Extracellular vesicles …

The importance of accurately correcting for the natural abundance of stable isotopes

FS Midani, ML Wynn, S Schnell - Analytical biochemistry, 2017 - Elsevier
The use of isotopically labeled tracer substrates is an experimental approach for measuring
in vivo and in vitro intracellular metabolic dynamics. Stable isotopes that alter the mass but …

Fluxomics links cellular functional analyses to whole-plant phenotyping

C Salon, JC Avice, S Colombié… - Journal of …, 2017 - academic.oup.com
Fluxes through metabolic pathways reflect the integration of genetic and metabolic
regulations. While it is attractive to measure all the mRNAs (transcriptome), all the proteins …

Comprehensive and accurate tracking of carbon origin of LC-tandem mass spectrometry collisional fragments for 13C-MFA

J Kappelmann, B Klein, P Geilenkirchen… - Analytical and …, 2017 - Springer
In recent years the benefit of measuring positionally resolved 13 C-labeling enrichment from
tandem mass spectrometry (MS/MS) collisional fragments for improved precision of 13 C …

To be certain about the uncertainty: Bayesian statistics for 13C metabolic flux analysis

A Theorell, S Leweke, W Wiechert… - Biotechnology and …, 2017 - Wiley Online Library
Abstract 13C Metabolic Fluxes Analysis (13C MFA) remains to be the most powerful
approach to determine intracellular metabolic reaction rates. Decisions on strain …