Eukaryotic cells determine the final protein output of their genetic program not only by
controlling transcription but also by regulating the localization, translation and turnover rates …

Cells are highly organized entities that rely on intricate addressing mechanisms to sort their
constituent molecules to precise subcellular locations. These processes are crucial for cells …

Cancer stem cells (CSCs) can regenerate all facets of a tumour as a result of their stem cell-
like capacity to self-renew, survive and become dormant in protective microenvironments …

RNA modifications are ubiquitous in biology, with over 100 distinct modifications. While the
vast majority were identified and characterized on abundant noncoding RNA such as tRNA …

Cytokines and growth factors regulate cell proliferation, differentiation, migration and
apoptosis, and play important roles in coordinating growth signal responses during …

Over the past several decades, the biology of the developing lens has been investigated
using molecular genetics-based approaches in various vertebrate model systems. These …

Some long noncoding RNAs (lncRNAs) can regulate gene expression programs, in turn
affecting specific cellular processes. We sought to identify the mechanism through which the …

RNA regulation provides a finely tuned and highly co-ordinated control of gene expression.
Regulation is mediated by hundreds to thousands of multi-functional RNA-binding proteins …

Post-transcriptional processes orchestrate gene expression through dynamic protein-RNA
interactions. These interactions occur at specific sites determined by RNA sequence …

With a long history in project management practices, project performance measurement
(PPM) offers a wide range of methods and good practices which help project managers to …