Chronic diseases, including obesity, are major causes of morbidity and mortality in most
countries. The adverse impacts of obesity and associated comorbidities on health remain a …

The concept that interactions between nutrition and genetics determine phenotype was
established by Garrod at the beginning of the 20th century through his ground-breaking …

Background Salivary (AMY1) and pancreatic (AMY2) amylases hydrolyze starch. Copy
number of AMY1A (encoding AMY1) was reported to be higher in populations with a high …

Background Studies have shown conflicting associations between the salivary amylase
gene (AMY1) copy number and obesity. Salivary amylase initiates starch digestion in the …

Alpha‐amylase exists across taxonomic kingdoms with a deep evolutionary history of gene
duplications that resulted in several α‐amylase paralogs. Copy number variation (CNV) in …

Background Salivary amylase in humans is encoded by the copy variable gene AMY1 in the
amylase gene cluster on chromosome 1. Although the role of salivary amylase is well …

Diet-related adaptive gene (DRAG) polymorphisms identified in specific populations are
associated with chronic disorders in carriers of the adaptive alleles due to changes in dietary …

Context Only a few genetic causes for childhood obesity have been identified to date. Copy
number variants (CNVs) are known to contribute to obesity, both syndromic (15q11. 2 …

Salivary and pancreatic amylases (encoded by AMY1 and AMY2 genes, respectively) are
responsible for digesting starchy foods. AMY1 and AMY2 show copy number variations that …

Grasses such as wheat and barley constitute some of the main crops currently cultivated
worldwide. Cultivation of wild cereals such as Hordeum spontaneum (wild barley) and …