Cells utilize diverse ATP-dependent nucleosome-remodelling complexes to carry out
histone sliding, ejection or the incorporation of histone variants, suggesting that different …

Advances in genomics technology have provided the means to probe myriad chromatin
interactions at unprecedented spatial and temporal resolution. This has led to a profound …

The establishment and maintenance of chromatin states involves multiscale dynamic
processes integrating transcription factor and multiprotein effector dynamics, cycles of …

Chromatin remodelers use a helicase-like ATPase motor to reposition and reorganize
nucleosomes along genomic DNA. Yet, how the ATPase motor communicates with other …

Chromatin remodelers are ATP-dependent enzymes that are critical for reorganizing and
repositioning nucleosomes in concert with many basic cellular processes. For the …

Eukaryotic genomes are functionally organized into chromatin, a compact packaging of
nucleoproteins with the basic repeating unit known as the nucleosome. A major focus for the …

The replisome is a multiprotein molecular machinery responsible for the replication of DNA.
It is composed of several specialized proteins each with dedicated enzymatic activities, and …

Chromatin remodelling proteins support a variety of cellular functions and utilise the energy
from ATP hydrolysis to either reposition or evict nucleosomes. One such protein, Lymphoid …

To date, gene expression has been characterized in over one thousand species across
more than a million experimental conditions. With this wealth of data, it is possible to …

The results of this work stem from the collaborative efforts of the labs from PD Dr. Philipp
Korber, Prof. B. Franklin Pugh, PhD., Prof. Craig L. Peterson, PhD., and Prof. Dr. Karl-Peter …