The forced swim test (FST) measures coping strategy to an acute inescapable stress and
thus provides unique insight into the neural limb of the stress response. Stress, particularly …

It is now well established that all clinically available antidepressants share a common
aptitude: they increase the production of adult-generated neurons in the dentate gyrus of the …

Abundant evidence connects depression symptomology with immune system activation,
stress and subsequently elevated levels of kynurenine. Anti-depressants, such as the …

This study presents anxiolytic-and antidepressant-like effects of a methanolic extract of
Morinda citrifolia Linn.(noni) fruit (MMC) in well-established mouse models of anxiety and …

Cannabis sativa is one of the most widely recreational drugs and its use is more prevalent
among depressed patients. Some studies reported that Cannabis has antidepressant effects …

The aim of the present study was to investigate the involvement of the monoaminergic
system in antidepressant-like effects of a characterized ethanolic extract of Mentha piperita …

The tachykinin NK1 receptor was suggested to be involved in psychiatric disorders, but its
antagonists have failed to be effective as antidepressants in clinical trials. Hemokinin-1 (HK …

Some clinical studies indicate that scopolamine may induce a rapid antidepressant effect.
Although scopolamine is a muscarinic antagonist, it seems that not only cholinergic but also …

Depression is a common mental disorder that affects millions of individuals worldwide.
Available monoaminergic antidepressants are far from ideal since they show delayed onset …

The genus Passiflora is popularly used to treat anxiety. Recent studies showed
antidepressant-like effects of two varieties of P. edulis (edulis and flavicarpa) in mice …