Children with congenital heart disease (CHD) are at increased risk of neurodevelopmental
disorders (NDDs) and psychiatric conditions. These include cognitive, adaptive, motor …

Objectives: Schizophrenia is a severe psychiatric disease affecting about 1% of the general
population. The relative contribution of genetic factors has been estimated to be up to 80 …

Schizophrenia (SZ) is a debilitating brain disorder with a complex genetic architecture.
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …

We undertook an RNA sequencing (RNAseq)-based transcriptomic profiling study on
lymphoblastoid cell lines of a European ancestry sample of 529 schizophrenia cases and …

Abstract NDE1 (Nuclear Distribution Element 1, also known as NudE) and NDEL1 (NDE-
Like 1, also known as NudEL) are the mammalian homologues of the fungus nudE gene …

Alzheimer's disease (AD) is a devastating disease mainly afflicting elderly people,
characterized by decreased cognition, loss of memory, and eventually death. Although risk …

Chromosomal microarray (CMA) is now recognized as the first-tier genetic test for detection
of copy number variations (CNVs) in patients with autism spectrum disorder (ASD). The aims …

Schizophrenia is a devastating neuropsychiatric disorder affecting approximately 1% of the
global population, and the disease has imposed a considerable burden on families and …

Cortical neurogenesis is a fundamental process of brain development that is
spatiotemporally regulated by both intrinsic and extrinsic cues. Although recent evidence …

Background Microcephaly is a disorder characterized by severe impairment in brain
development, reduced brain and head size. Congenital severe microcephaly is very rare …