Diagnosing antiphospholipid syndrome:'extra-criteria'manifestations and technical advances

S Sciascia, MC Amigo, D Roccatello… - Nature Reviews …, 2017 - nature.com
First described in the early 1980s, antiphospholipid syndrome (APS) is a unique form of
acquired autoimmune thrombophilia in which patients present with clinical features of …

Antiphospholipid syndrome: role of vascular endothelial cells and implications for risk stratification and targeted therapeutics

MT Corban, A Duarte-Garcia, RD McBane… - Journal of the American …, 2017 - jacc.org
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by venous
thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently …

The antiphospholipid syndrome: from pathophysiology to treatment

S Negrini, F Pappalardo, G Murdaca, F Indiveri… - Clinical and …, 2017 - Springer
Antiphospholipid antibody syndrome (APS) is an autoimmune acquired thrombophilia
characterized by recurrent thrombosis and pregnancy morbidity in the presence of …

Pathogenesis and management of antiphospholipid syndrome

DRJ Arachchillage, M Laffan - British journal of haematology, 2017 - Wiley Online Library
Antiphospholipid antibodies are a heterogeneous group of autoantibodies that have clear
associations with thrombosis and pregnancy morbidity, and which together constitute the …

Diagnosis and management of the antiphospholipid syndrome

S Chaturvedi, KR McCrae - Blood reviews, 2017 - Elsevier
Antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy
complications in the presence of persistent antiphospholipid antibodies (APLA). Laboratory …

Clinical significance of anti-domain 1 β2-glycoprotein I antibodies in antiphospholipid syndrome

T Iwaniec, MP Kaczor, M Celińska-Löwenhoff… - Thrombosis …, 2017 - Elsevier
Background Antiphospholipid syndrome (APS) is characterized by the presence of
circulating antiphospholipid antibodies (aPL) in patients with thrombosis and/or pregnancy …

Cardiovascular risk factors are major determinants of thrombotic risk in patients with the lupus anticoagulant

F Posch, J Gebhart, JH Rand, S Koder… - BMC medicine, 2017 - Springer
Background Patients with the lupus anticoagulant (LA) are at an increased risk of thrombotic
events, which in turn increase the risk of death. Understanding the determinants of …

Potential influences of complement factor H in autoimmune inflammatory and thrombotic disorders

J Ferluga, L Kouser, V Murugaiah, RB Sim… - Molecular …, 2017 - Elsevier
Complement system homeostasis is important for host self-protection and anti-microbial
immune surveillance, and recent research indicates roles in tissue development and …

Lupus anticoagulant testing: diluted Russell viper venom time (dRVVT)

V Pengo, E Bison, A Banzato, G Zoppellaro… - … : Methods and Protocols, 2017 - Springer
Abstract Diluted Russell Viper Venom Time (dRVVT) has become the most popular test to
detect Lupus Anticoagulant (LA). dRVVT is more sensitive than other global tests employed …

How to identify high-risk APS patients: clinical utility and predictive values of validated scores

K Oku, O Amengual, S Yasuda, T Atsumi - Current Rheumatology Reports, 2017 - Springer
Abstract Purpose of Review Antiphospholipid syndrome (APS) is a clinical disorder
characterised by thrombosis and/or pregnancy morbidity in the persistence of …