Genetics of generalized anxiety disorder and related traits

MG Gottschalk, K Domschke - Dialogues in clinical neuroscience, 2017 - Taylor & Francis
This review serves as a systematic guide to the genetics of generalized anxiety disorder
(GAD) and further focuses on anxiety-relevant endophenotypes, such as pathological worry …

Life stress, glucocorticoid signaling, and the aging epigenome: Implications for aging-related diseases

NC Gassen, GP Chrousos, EB Binder… - … & Biobehavioral Reviews, 2017 - Elsevier
Life stress has been associated with accelerated cellular aging and increased risk for
developing aging-related diseases; however, the underlying molecular mechanisms remain …

[HTML][HTML] The relationship between childhood psychosocial stressor level and telomere length: a meta-analysis

LM Hanssen, NS Schutte, JM Malouff… - Health psychology …, 2017 - ncbi.nlm.nih.gov
This meta-analysis examined the association between the level of childhood psychosocial
stressors and telomere length, an important health biomarker. The meta-analysis, including …

The telomere lengthening conundrum–it could be biology

M Bateson, D Nettle - Aging Cell, 2017 - Wiley Online Library
Longitudinal studies of human leucocyte telomere length often report a percentage of
individuals whose telomeres appear to lengthen. However, based on theoretical …

Posttraumatic stress disorder and accelerated aging: PTSD and leukocyte telomere length in a sample of civilian women

AL Roberts, KC Koenen, Q Chen… - Depression and …, 2017 - Wiley Online Library
Background Studies in male combat veterans have suggested posttraumatic stress disorder
(PTSD) is associated with shorter telomere length (TL). We examined the cross‐sectional …

Association between childhood trauma and accelerated telomere erosion in adulthood: a meta-analytic study

Z Li, Y He, D Wang, J Tang, X Chen - Journal of psychiatric research, 2017 - Elsevier
Background Childhood trauma has long-term sequelae on health status and contributes to
numbers of somatic and mental disorders in later life. Findings from experimental studies in …

A meta-analysis of the relationship between anxiety and telomere length

JM Malouff, NS Schutte - Anxiety, Stress, & Coping, 2017 - Taylor & Francis
Background and objectives: Telomeres are protective caps at the ends of chromosomes,
and shorter telomeres are associated with poor physical health. The present study set out to …

[HTML][HTML] Assessing the contributions of childhood maltreatment subtypes and depression case-control status on telomere length reveals a specific role of physical …

J Vincent, I Hovatta, S Frissa, L Goodwin… - Journal of affective …, 2017 - Elsevier
Background Studies have provided evidence that both childhood maltreatment and
depressive disorders are associated with shortened telomere lengths. However, as …

Intrauterine exposure to maternal stress alters Bdnf IV DNA methylation and telomere length in the brain of adult rat offspring

J Blaze, A Asok, K Borrelli, C Tulbert, J Bollinger… - International Journal of …, 2017 - Elsevier
DNA methylation (addition of methyl groups to cytosines) and changes in telomere length
(TTAGGG repeats on the ends of chromosomes) are two molecular modifications that result …

The implications of war captivity and long-term psychopathology trajectories for telomere length

Z Solomon, N Tsur, Y Levin, O Uziel, M Lahav… - …, 2017 - Elsevier
Background Previous findings have demonstrated the link between trauma, its
psychopathological aftermath and cellular aging, as reflected in telomere length. However …