Design, synthesis and cytotoxic effects of curcuminoids on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines

SNH Zamrus, MN Akhtar, SK Yeap, CK Quah… - Chemistry Central …, 2018 - Springer
Background Curcumin is one of the leading compound extracted from the dry powder of
Curcuma longa (Zingiberaceae family), which possess several pharmacological properties …

Design, synthesis and identification of novel substituted isothiochromene analogs as potential antiviral and cytotoxic agents

AA Abu-Hashem, MA Gouda, FA Badria - Medicinal Chemistry Research, 2018 - Springer
In this study, we present the synthesis of novel isothiochromenes, thiazolidonone,
thiazinone, arylidines, triazoles, and pyrimidinone compounds based on the starting material …

Anticancer potential of novel curcumin analogs towards castrate-resistant prostate cancer

S Chen, M Nimick, AG Cridge… - International …, 2018 - spandidos-publications.com
Prostate cancer is initially sensitive to hormone therapy; however, over time the majority of
patients progress to a hormone-insensitive form classified as castration-resistant prostate …

[PDF][PDF] Multifaceted Role of a Marvel Golden Molecule, Curcumin: a Review.

SS Moselhy, S Razvi, N Hasan… - Indian journal of …, 2018 - researchgate.net
Curcumin is chemically known as diferuloylmethane, which is an important nutraceutical
obtained from the yellow spice Curcuma longa. It has been used traditionally as a folklore …

Synthesis of benzimidazole-cyclohexanone derivatives

N Belkheiri, Z Belkacem, M Derdour… - Journal of Fundamental …, 2018 - ajol.info
This work reports the synthesis and characterization of new benzimidazole-cyclohexanone
derivatives 3a-d, 4a-d and 5a-d under different reaction conditions. The intermediates and …