Role of gut microbiota-generated short-chain fatty acids in metabolic and cardiovascular health

ES Chambers, T Preston, G Frost, DJ Morrison - Current nutrition reports, 2018 - Springer
Abstract Purpose of this Review This review assesses the latest evidence linking short-chain
fatty acids (SCFA) with host metabolic health and cardiovascular disease (CVD) risk and …

The gut microbiota as a novel regulator of cardiovascular function and disease

ML Battson, DM Lee, TL Weir, CL Gentile - The Journal of nutritional …, 2018 - Elsevier
The gut microbiome has emerged as a critical regulator of human physiology. Deleterious
changes to the composition or number of gut bacteria, commonly referred to as gut …

[HTML][HTML] Inulin-type fructan improves diabetic phenotype and gut microbiota profiles in rats

Q Zhang, H Yu, X Xiao, L Hu, F Xin, X Yu - PeerJ, 2018 - peerj.com
Methods A diabetic rat model was generated by a high-fat diet and streptozotocin injections
(HF/STZ). Inulin was orally administered to normal and diabetic rats. To determine the …

[HTML][HTML] Assessing the effect of high performance inulin supplementation via KLF5 mRNA expression in adults with type 2 diabetes: a randomized placebo controlled …

A Ghavami, N Roshanravan, S Alipour… - Advanced …, 2018 - ncbi.nlm.nih.gov
Purpose: The worldwide prevalence of metabolic disorders such as diabetes is increasing
rapidly. Currently, the complications of diabetes are the major health concern. The aim of …

[HTML][HTML] Targeted intestinal delivery of incretin secretagogues—towards new diabetes and obesity therapies

FM Gribble, CL Meek, F Reimann - Peptides, 2018 - Elsevier
A new strategy under development for the treatment of type 2 diabetes and obesity is to
mimic some of the effects of bariatric surgery by delivering food-related stimuli to the distal …

Synthesis, characterization of inulin propionate ester, and evaluation of its in vitro effect on SCFA production

X Zhu, C Jia, X Meng, M Xing, Y Yi, X Gao - Starch‐Stärke, 2018 - Wiley Online Library
In this study, the authors developed a method for the synthesis of inulin propionate ester as
dietary fiber carrier to increase the amounts of short chain fatty acids (SCFA). The …

高血糖“代谢记忆” 治疗策略的研究进展

尹航, 梁爽, 何华, 柳晓泉 - 药学进展, 2018 - pps.cpu.edu.cn
临床研究表明, 早期强化降血糖治疗可显著改善高血糖“代谢记忆” 效应, 并降低糖尿病患者血管
并发症发病风险. 大量证据亦表明高血糖“代谢记忆” 的发生可能与蛋白质非酶糖基化 …

Progress in therapeutic strategy for high glucose-induced metabolic memory

YIN Hang, L Shuang, HE Hua… - Progress in …, 2018 - pps.cpu.edu.cn
Clinical studies have suggested that early intensive control of hyperglycaemia could
ameliorate high glucose-induced" metabolic memory", and decrease the risk of diabetic …

[引用][C] Immune modulation by microbiota sources: effects of aloe vera gel and butyrate

A Yagi, BP Yu - Journal of Gastroenterology and Hepatology Research, 2018