Nucleic acid-based therapeutics present huge potential in the treatment of pulmonary
diseases ranging from lung cancer to asthma and chronic pulmonary diseases, which are …

With recent advances in the field of RNAi-based therapeutics, it is possible to make any
target gene 'druggable', at least in principle. The present review focuses on aspects critical …

The therapeutic potential of small nucleic acids such as small interfering RNA (siRNA) to
treat lung diseases has been successfully demonstrated in many in vivo studies. A major …

Spray freeze drying is an attractive technology to produce powder formulation for inhalation.
It can be used to generate large porous particles which tend to aerosolize efficiently and do …

Gene therapy is a breakthrough treatment strategy against several intractable and lethal
diseases that previously lacked established treatments. Viral and nonviral vectors have …

Chronic obstruction pulmonary disease (COPD) is a major cause of morbidity and mortality
across the world. COPD is currently the fourth leading cause of death in the world and is …

Tuberculosis (TB) remains the infectious disease with the highest mortality alongside HIV.
Despite the existence of the Bacillus Calmette-Guerin (BCG) vaccine there is an unmet need …

Respiratory diseases such as asthma or infections are often attributed to the (over)
expression of disease-causing genes. Exploiting RNA interference (RNAi), local …