The central nervous system (CNS) is an immunologically specialized tissue protected by a
blood–brain barrier. The CNS parenchyma is enveloped by a series of overlapping …

Central nervous system (CNS) injuries, such as stroke, traumatic brain injury (TBI) and
spinal cord injury (SCI), are important causes of death and long-term disability worldwide …

Abstract Introduction Ischemia/reperfusion (I/R) injury, such as myocardial infarction, stroke,
and peripheral vascular disease, has been recognized as the most frequent causes of …

Stroke is a devastating disease that afflicts millions of people each year worldwide. Ischemic
stroke, which accounts for~ 88% of cases, occurs when blood supply to the brain is …

Background The treatment of acute ischemic stroke due to large vessel occlusion (LVO) has
revolutionized in the last decade. We sought to compile the most relevant literature …

Preclinical and clinical studies support a promising, albeit not definitive, neuroprotective
effect of emergent uric acid (UA) administration in ischemic stroke. We assessed the effects …

Objective Leukocytes play a crucial role in inflammation and immune response. This study
aims to demonstrate the value of changes in leukocytes levels 24 hours after intravenous …

Aim: Our previous study demonstrated miR-122 mimic decreased NOS2 expression in blood
leucocytes and improved stroke outcomes when given immediately after middle cerebral …

Background This study assessed whether serum lipid levels are associated with the risk of
symptomatic intracerebral hemorrhage (sICH) and functional outcomes in patients with …

Reperfusion therapy using intravenous thrombolysis 2 and mechanical thrombectomy 2, 3
are the only approved treatments for acute ischaemic stroke, but must be administered in a …