New technologies for analysis of extracellular vesicles

H Shao, H Im, CM Castro, X Breakefield… - Chemical …, 2018 - ACS Publications
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

[HTML][HTML] Mother's milk: a purposeful contribution to the development of the infant microbiota and immunity

K Le Doare, B Holder, A Bassett… - Frontiers in …, 2018 - frontiersin.org
Breast milk is the perfect nutrition for infants, a result of millions of years of evolution. In
addition to providing a source of nutrition, breast milk contains a diverse array of microbiota …

[HTML][HTML] Technical challenges of working with extracellular vesicles

MI Ramirez, MG Amorim, C Gadelha, I Milic, JA Welsh… - Nanoscale, 2018 - pubs.rsc.org
Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …

Preservation and storage stability of extracellular vesicles for therapeutic applications

A Jeyaram, SM Jay - The AAPS journal, 2018 - Springer
Abstract Recently, extracellular vesicles (EVs)—including exosomes, microvesicles, and
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …

Biocompatibility of highly purified bovine milk-derived extracellular vesicles

M Somiya, Y Yoshioka, T Ochiya - Journal of extracellular vesicles, 2018 - Taylor & Francis
Extracellular vesicles (EVs) deliver biologically active cargos from donor cells to recipient
cells for intercellular communication. Since the existence of RNA cargo was discovered, EVs …

Subpopulations of extracellular vesicles and their therapeutic potential

C Lässer, SC Jang, J Lötvall - Molecular aspects of medicine, 2018 - Elsevier
Extracellular vesicles (EVs), such as exosomes and microvesicles, have over the last 10–15
years been recognized to convey key messages in the molecular communication between …

[HTML][HTML] “Exosomics”—a review of biophysics, biology and biochemistry of exosomes with a focus on human breast milk

C de la Torre Gomez, RV Goreham… - Frontiers in …, 2018 - frontiersin.org
Exosomes are biomolecular nanostructures released from cells. They carry specific
biomolecular information and are mainly researched for their exquisite properties as a …

[HTML][HTML] Abundantly present miRNAs in milk-derived extracellular vesicles are conserved between mammals

MJC Herwijnen, TAP Driedonks, BL Snoek… - Frontiers in …, 2018 - frontiersin.org
Mammalian milk is not only a source of nutrition for the newborn, but also contains various
components that regulate further development. For instance, milk is an abundant source of …

Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography

AD Foers, S Chatfield, LF Dagley… - Journal of …, 2018 - Taylor & Francis
As a complex biological fluid, human synovial fluid (SF) presents challenges for extracellular
vesicle (EV) enrichment using standard methods. In this study of human SF, a size exclusion …

[HTML][HTML] Exosomes and miRNA-loaded biomimetic nanovehicles, a focus on their potentials preventing type-2 diabetes linked to metabolic syndrome

D Beuzelin, B Kaeffer - Frontiers in immunology, 2018 - frontiersin.org
Exosomes are small membrane vesicles of 30–150 nm, members of the extracellular vesicle
family and secreted by various cell types. Different studies describe specific microRNA …